Hearing

Navigating the Genome to Cure Deafness

A new Tel Aviv University study solves a critical piece of the puzzle of human deafness by identifying the first group of long non-coding RNAs (lncRNAs) in the auditory system. "The research on long non-coding RNAs is crucial to understanding how gene expression and regulatory elements influence the auditory system," says Prof. Karen Avraham, Vice

November 11th, 2017|Categories: Disease Specific, Hearing|Tags: , |

New technique generates high volume of sensory cells needed for hearing

FEBRUARY 21, 2017 A two-step process of multiplying stem cells found in the inner ear and converting them to hair cells may restore hearing lost to age, noise damage and other factors.Media Contact: Suzanne Day Media Relations Manager, Mass. Eye and Ear 617-573-3897 Boston, Mass. — The loss of tiny, sound-sensing cells in the inner ear, known as “hair

February 21st, 2017|Categories: Hearing|Tags: , , , |

Researchers launch first clinical trial for Wolfram syndrome

Many people with rare genetic disease die prematurely by Jim Dryden•November 10, 2016 The drug dantrolene is a muscle relaxant approved to treat patients with cerebral palsy, multiple sclerosis and muscle spasticity. Recent research also suggests it can prevent the destruction of insulin-secreting beta cells in animal models of Wolfram syndrome. Researchers at Washington University

Stem Cell Discovery Might Lead to Fix for Gene Mutation Behind Hereditary Hearing Loss

A new study in STEM CELLS Translational Medicine offers people with genetic hearing loss the promise of a new therapy that just might outperform artificial cochlear implants.  DURHAM, NC (PRWEB) MARCH 31, 2016 A new study in STEM CELLS Translational Medicine offers people with genetic hearing loss the promise of a new therapy that just

Army Tests Hearing Drug at the Rifle Range

(The Wall Street Journal via NewsPoints Desk) (Ref: The Wall Street Journal) August 21st, 2015 The Wall Street Journal reported that a trial being conducted in collaboration with the US military is testing an experimental drug that might prevent noise-induced hearing loss. The compound, a liquid form of d-methionine, was developed into a drug by

Orchestrating hair cell regeneration: a supporting player’s close-up

Jul 16 2015 KANSAS CITY, MO—The older we get, the less likely we are to hear well, as our inner ear sensory hair cells succumb to age or injury. Intriguingly, humans are one-upped by fish here. Similar hair cells in a fish sensory system that dots their bodies and forms the lateral line, by which

OHSU scientists unlock first critical step toward gene therapy treatment for patients with mitochondrial disease

07/15/15  Portland, Ore. Gene-based cures for human diseases are now on the horizon A study led by Shoukhrat Mitalipov, Ph.D., and Hong Ma, M.D., Ph.D., at the Center for Embryonic Cell and Gene Therapy at Oregon Health & Science University and the Oregon National Primate Research Center has revealed the first critical step in developing novel

New findings hint toward reversing hearing loss

July 15, 2015 By Julia Evangelou Strait SUNG-HO HUH PHOTO A normal mouse cochlea shows a characteristic spiral shape. Unlike birds and amphibians, mammals can’t recover lost hearing. In people, the cells of the inner ear responsible for detecting sound and transmitting those signals to the brain form during early stages of development and can’t

Found: A Likely New Contributor to Age-Related Hearing Loss

New nerve cell connections on sensory cells in mice could be at fault July 13, 2015 FAST FACTS: Hair cells in the inner ear “sense” sound waves and convert them to electrical signals sent via outgoing nerve cells to the brain. With aging, some hair cells die, contributing to hearing loss. New connections between certain

Is Boston Children’s Hospital on its way to curing genetic deafness?

Jul 8, 2015, 1:08pm EDT Jessica Bartlett Boston Business Journal COURTESY/ POCKAFWYE VIA CREATIVE COMMONS ​Researchers used gene therapy to restore hearing in mice with a genetic form of… more Researchers at Boston Children’s Hospital and Harvard Medical School have used gene therapy to restore hearing in mice with a genetic form of deafness. The