Muscular Dystrophy

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In Lab Research, Scientists Slow Progression of a Fatal Form of Muscular Dystrophy

In a paper published in the Nature journal Scientific Reports, Saint Louis University researchers report that a new drug reduces fibrosis (scarring) and prevents loss of muscle function in an animal model of Duchenne muscular dystrophy (DMD), providing a promising approach in designing new medications for those suffering from DMD. DMD is a fatal form of

SLU Researcher Draws Bulls Eye Around Muscular Dystrophy Drug Targets

In a recent paper published in the journal Skeletal Muscle, a Saint Louis University researcher reports success in identifying new drug targets that potentially could slow or halt the progression of a form muscular dystrophy, an illness characterized by progressive muscle degeneration. Francis M. Sverdrup, Ph.D., research fellow in the Saint Louis University Department of Biochemistry and

Scientists speed up muscle repair – could fight dystrophy

Wednesday, October 05, 2016 Baltimore, MD---Athletes, the elderly and those with degenerative muscle disease would all benefit from accelerated muscle repair. When skeletal muscles, those connected to the bone, are injured, muscle stem cells wake up from a dormant state and repair the damage. When muscles age, however, stem cell number and function declines, as

Scientists find way to create human stem cells with only 23 chromosomes, could revolutionize genetic research

BY DENIS SLATTERY, NEW YORK DAILY NEWS, Wednesday, March 16, 2016, 8:53 PM A scientific discovery unveiled Wednesday could revolutionize genetic research with new screening tools and therapies. Researchers from Columbia University Medical Center, the New York Stem Cell Foundation Research Institute and Hebrew University have found a way to create human stem cells with only 23

Researchers resolve longstanding issue of components needed to regenerate muscle

By Susan Gammon, Ph.D. February 9, 2016 Researchers at SBP have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle. The discovery clears up deep-rooted conflicting data and will now help streamline efforts towards boosting stem cell-mediated muscle regeneration. Such strategies could treat muscle degenerative diseases such as muscular dystrophies,

Gene Therapy Treats All Muscles in the Body in Muscular Dystrophy Dogs; Human Clinical Trials Are Next Step

Oct. 22, 2015 Story Contact: Christian Basi COLUMBIA, Mo. ­— Muscular dystrophy, which affects approximately 250,000 people in the U.S., occurs when damaged muscle tissue is replaced with fibrous, fatty or bony tissue and loses function. For years, scientists have searched for a way to successfully treat the most common form of the disease, Duchenne Muscular Dystrophy

Researchers Isolate Human Muscle Stem Cells

By Nicholas Weiler on September 22, 2015 UC San Francisco researchers have successfully isolated human muscle stem cells and shown that the cells could robustly replicate and repair damaged muscles when grafted onto an injured site. The laboratory finding paves the way for potential treatments for patients with severe muscle injury, paralysis or genetic diseases

Engineering a permanent solution to genetic diseases

Aug. 10, 2015 - In his mind, Basil Hubbard can already picture a new world of therapeutic treatments for millions of patients just over the horizon. It’s a future in which diseases like muscular dystrophy, cystic fibrosis and many others are treated permanently through the science of genome engineering. Thanks to his latest work, Hubbard

Potential treatment for muscular dystrophy

Harvard Gazette, by Hadley Bridger, Brigham & Women's Hospital ~ August 3, 2015 Skeletal muscle is one of the most abundant tissue types in the human body, but it has proven difficult to produce in large quantities in the lab. Unlike other cell types, such as heart cells, neurons, and cells found in the gut,

A New Grasp on Robotic Glove

Mon, 06/08/2015 - 10:15am- Harvard University The soft robotic glove could help patients suffering from muscular dystrophy, amyotrophic lateral sclerosis, incomplete spinal cord injury, or other hand impairments regain some independence and control of their environment. (Photo: Courtesy of Wyss Institute at Harvard University)Having achieved promising results in proof-of-concept prototyping and experimental testing, a soft robotic