A Potential Cause of CAR T Side Effects, and A Path Forward Chimeric antigen receptor (CAR) T cell therapy has revolutionized treatment of leukemia, lymphoma, and multiple myeloma. But some people who have received this treatment experience neurotoxicity, or damage to the brain or nervous system. Read more...
Immune Modulator Drugs for COVID-19 Focus of Major NIH Clinical Trial One of the most vexing aspects of the COVID-19 pandemic is the novel coronavirus’s ability to turn the body’s immune system against the body. After the virus has been cleared from the body, the immune system sometimes continues to
Stem Cells Can Repair Parkinson’s-Damaged Circuits in Mouse Brains The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson’s. Stem cells, which are endlessly adaptable, have offered the promise of better neural repair. But the brain’s
Missouri S&T Receives $300 Million Gift for Research and Innovation Center In the largest single gift in the history of Missouri higher education, St. Louis businessman Fred Kummer and his wife June have donated $300 million to a foundation that will support Missouri S&T, the university announced today. Read more...
Cerebral Palsy Also Has Genetic Underpinnings The causes of cerebral palsy have long been debated and often are attributed to in utero infections, premature birth, or brain injury to the baby near or during delivery, usually from a lack of oxygen. But many young children diagnosed with cerebral palsy have
Antibodies Protect Against Wide Range of Influenza B Virus Strains Researchers have identified two antibodies that protect mice against lethal infections of influenza B virus, report scientists at Washington University School of Medicine in St. Louis and Icahn School of Medicine at Mount Sinai. Together with an antibody that targets
Leading the Way: MU researcher Salman Hyder Has Spent a Career Battling Breast Cancer and Mentoring the Next Generation of Researchers Salman Hyder has spent nearly two decades at the University of Missouri researching ways to stop the spread of breast cancer. Among his greatest discoveries was that combined hormone replacement
First Immune-Evading Cells Created to Treat Type 1 Diabetes Salk Institute scientists have made a major advance in the pursuit of a safe and effective treatment for type 1 diabetes, an illness that impacts an estimated 1.6 million Americans with a cost of $14.4 billion annually. Read more...
Coronavirus Reinfections: Three Questions Scientists Are Asking When news broke last week that a man living in Hong Kong had been infected with the coronavirus again, months after recovering from a previous bout of COVID-19, immunologist Akiko Iwasaki had an unusual reaction. “I was really kind of happy,” she says.
Research Reveals Another Possible Epstein-Barr Virus Link to MS Over the years, many studies have looked at a possible EBV-MS connection. One of the latest was published earlier this year, with researchers reporting that the interaction between certain genes and the virus is “consistent with an EBV susceptibility signature contributing to