A Joint ‘Replacement’ Without Surgery? It’s on the Horizon A sports injury or trauma to cartilage around the knee, hip or shoulder joint can lead to osteoarthritis later in life—or, worse yet, the need for a new joint. So can the wear and tear that comes with age. One day,
Research Reveals How Subtle Changes in a microRNA May Lead to ALS When people think about the connection between genes and disease, they often envision something that works like a light switch: When the gene is normal, the person carrying it does not have the disease. If it gets mutated,
Sickle-Cell Disease Every parent or carer wants the best for their children, but sometimes biological miscues obstruct that universal hope. This is especially the case with sickle-cell disease, a disorder in which red blood cells take on an abnormal shape described as a crescent or sickle. This malformation restricts oxygen
Scans Show the Physical Marks of Poverty on Kids Brains Children in poverty are more likely to have cognitive and behavioral difficulties than their better-off peers. Plenty of past research has looked into the physical effects of childhood poverty, or documented mental health disparities between socioeconomic classes. Read more...
Cat in the Lab: Feline Genomes Fuel Precision Medicine When one thinks of the most popular and useful animal models in biomedical research, one thinks of mice and rats, followed by rabbits, dogs, monkeys, and so on. The domestic cat is traditionally a long way down the list. But a
Research to Explore How Genes, Other Factors Affect Cardiometabolic Disease Risk Researchers at Washington University School of Medicine in St. Louis have received a four-year, $8.8 million grant to ramp up research aimed at unraveling how an individual’s risks of cardiometabolic diseases, such as heart disease and Type 2 diabetes,
‘Good Cholesterol’ May Protect Liver The body’s so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown role in protecting the liver from injury. This HDL protects
The Future of Pancreatic Cancer Treatment: It’s Personal A decade ago, the survival rate for pancreatic cancer hovered around five percent. Today, the five-year survival rate is 10 percent. “We’ve moved into the double-digits, but there is clearly an urgent need to find better therapies to treat cancer of the
Saint Luke’s Clinical Trial Shows Improvements in Patients with Common Genetic Heart Condition Saint Luke’s Mid America Heart Institute announced the results of a clinical trial that will impact patient care and improve quality of life for patients suffering from the most common genetic heart condition, called hypertrophic cardiomyopathy (HCM).
A Look at “Eyes on the Brain Organoids” Cell Stem Cell Paper At first glance, I thought they grew the brain organoids and the “eyes” separately and then grafted the eyes onto the brain organoids or had taken an “assembloid” approach. But no. It seems they were able to generate