Around The State

Home/Around The State

Stem cells edited to fight arthritis

Goal is vaccine that targets inflammation in joints by Jim Dryden•April 27, 2017 ELLA MARUSHCHENKO Using CRISPR technology, a team of researchers led by Farshid Guilak, PhD, at Washington University School of Medicine in St. Louis, rewired stem cells' genetic circuits to produce an anti-inflammatory arthritis drug when the cells encounter inflammation. The technique eventually

Antibody helps detect protein implicated in Alzheimer’s, other diseases

May lead to novel ways to diagnose, monitor brain injury by Tamara Bhandari•April 19, 2017 HUY MACH Researchers use mouse brains (above) to study ways to measure the brain protein tau, which plays a role in neurodegenerative diseases such as Alzheimer's. A team led by scientists at Washington University School of Medicine in St. Louis

Antibody helps detect protein implicated in Alzheimer’s, other diseases

May lead to novel ways to diagnose, monitor brain injury by Tamara Bhandari•April 19, 2017 HUY MACH Researchers use mouse brains (above) to study ways to measure the brain protein tau, which plays a role in neurodegenerative diseases such as Alzheimer's. A team led by scientists at Washington University School of Medicine in St. Louis

Could a Dog Vaccine Help Save Kids With Brain Cancer?

By: Laura Goldman, Care2.com, April 17, 2017 The statistics are grim: About 60 to 70 percent of children who have glioblastoma, a form of brain cancer, do not survive more than two years. This fast-growing cancer is resistant to traditional treatments like radiation and chemotherapy. For dogs, cancer statistics are also grim. More than 6

New imaging technique shows effectiveness of Cystic Fibrosis drug

April 15, 2017 by Deidra Ashley Talissa Altes, MD, Chair of the Department of Radiology at the MU School of Medicine. Hyperpolarized helium MRI could aid in development of improved therapies for lung diseases According to the Cystic Fibrosis Foundation, more than 30,000 Americans are living with the disorder. It currently has no cure, though a

Missouri Researchers Join Hunt For One Of Medicine’s Elusive Quarries: Artificial Blood

By ALEX SMITH • APR 5, 2017 Former railroad worker Johnnie Matz has been donating blood, platelets and plasma at the Community Blood Center in Kansas City for 45 years. ALEX SMITH / KCUR 89.3 Medical researchers have made a lot of progress developing artificial versions of organs like the heart, lungs and kidneys, but

Biomarker Could Lead to Personalized Therapies for Prostate Cancer

Protein testing could aid clinicians in the proper diagnosis and treatment of the disease April 05, 2017 Story Contact: Jeff Sossamon COLUMBIA, Mo. – In 2016, more than 181,000 new cases of prostate cancer were reported in the U.S., according to the American Cancer Society. The prostate-specific antigen (PSA) test is one of the earliest ways

$3.6 million to fund personalized 3-D brain maps to guide neurosurgeries

Academic-industry partnership aims to improve brain surgery By Tamara Bhandari April 5, 2017 Neurosurgeons must avoid cutting into parts of the brain responsible for key functions such as language (orange) and vision (green), but individuals vary in where such functions are located (each of the top images compared with the bottom images above). Researchers are creating

Rogue breast tumor proteins point to potential drug therapies

Such treatment options are missed by genomic sequencing By Julia Ezangelou Strait March 28, 2017 For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies. But this approach overlooks another potential marker — rogue proteins — that may

Surprising culprit in nerve cell damage identified

Findings suggest ways to block nerve cell damage in neurodegenerative diseases By Julia Evangelou Strait March 22, 2017 Nerve axons (left) serve as the electrical wiring of the nervous system. Scientists have implicated a specific molecule in triggering a self-destruct program in axons that leads to their degeneration (right). Since axonal degeneration is a common thread