Understanding How Cancer Can Relapse

Understanding How Cancer Can Relapse In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one of these mutations — oncogenic RAS or RASV12 —

Scientists Find Genetic Link to Clogged Arteries

Scientists Find Genetic Link to Clogged Arteries High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke. But now, scientists at Washington University School of Medicine in St. Louis have identified a gene that likely plays

Zika Virus Helps Destroy Deadly Brain Cancer in Mice

Zika Virus Helps Destroy Deadly Brain Cancer in Mice The Zika virus that ravaged the Americas, leaving many babies with permanent brain damage, may have a silver lining. The virus can activate immune cells to destroy an aggressive brain cancer in mice, giving a powerful boost to an immunotherapy drug

International Alzheimer’s Clinical Trial to Test Tau Drugs

International Alzheimer’s Clinical Trial to Test Tau Drugs A worldwide clinical trial aimed at finding treatments for Alzheimer’s disease has expanded to include investigational drugs targeting a harmful form of the brain protein tau. The trial, known as the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) and led by Washington

Developing a Targeted Delivery System to Treat Cancer

Developing a Targeted Delivery System to Treat Cancer In the ongoing battle to find ways to treat cancer, a team at the University of Missouri is addressing the problem from multiple angles, but with a precision approach. Cancer patients are often given chemotherapy, cancer-fighting drugs that kill cancerous cells and

A Niche for the Eye

A Niche for the Eye What if the degenerative eye conditions that lead to glaucoma, corneal dystrophy, and cataracts could be detected and treated before vision is impaired? Recent findings from the lab of Investigator Ting Xie, PhD, at the Stowers Institute for Medical Research point to the ciliary body

Scientists to Explore Whether Anti-Inflammatory Drugs Control Blood Sugar

Scientists to Explore Whether Anti-Inflammatory Drugs Control Blood Sugar Inflammation and metabolic disorders are deeply intertwined. For example, people with inflammatory conditions such as Crohn’s disease and psoriasis are at risk of developing metabolic disorders such as insulin resistance and diabetes. However troubling that connection might seem, it also might

Cats May Help Increase Empathy, Decrease Anxiety for Kids with Autism

Cats May Help Increase Empathy, Decrease Anxiety for Kids with Autism As a former school nurse in the Columbia Public Schools, Gretchen Carlisle would often interact with students with disabilities who took various medications or had seizures throughout the day. At some schools, the special education teacher would bring in

How Does the Immune System Keep Tabs on the Brain?

How Does the Immune System Keep Tabs on the Brain? Alzheimer’s disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain. There’s growing evidence that immune cells and molecules play a key role in normal brain development and function as