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Good News from Trio of Phase One Zika Vaccine Trials

In early results published in the Lancet, researchers report that an investigational Zika vaccine was well-tolerated and stimulated potentially protective immune responses in three phase 1 clinical trials, one of which was conducted at Saint Louis University. More than 90 percent of study volunteers in the three trials who received the investigational vaccine demonstrated an immune

December 7th, 2017|Categories: Around The State, Clinical Trials|Tags: , , |

NIH and partners launch HIV vaccine efficacy study

The National Institutes of Health and partners have launched a large clinical trial to assess whether an experimental HIV vaccine regimen is safe and able to prevent HIV infection. The new Phase 2b proof-of-concept study, called Imbokodo, aims to enroll 2,600 HIV-negative women in sub-Saharan Africa. Of 1.8 million new HIV infections worldwide in 2016,

December 1st, 2017|Categories: Clinical Trials, HIV|Tags: , |

Researchers turn to creative approaches to battle kidney stones

Can a high-tech water bottle help reduce the recurrence of kidney stones? What about a financial incentive? Those are questions researchers funded by the National Institutes of Health will seek to answer as they begin recruiting participants for a two-year clinical trial at four sites across the country. Scientists will test whether using a smart

September 15th, 2017|Categories: Clinical Trials, Kidney Disease|Tags: |

NIH Funds SLU Research of Possible Treatment for Drug-Resistant TB

Saint Louis University is leading a multi-national clinical trial of what could become a regimen for drug resistant tuberculosis (TB) that does not require injectable medications. The project is funded by a $6.4 million task order from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). Daniel

Oral Basal Insulin Shows Promise in Type 2 Diabetes

SAN DIEGO — An oral basal insulin formulation has produced glycemic control equivalent to that of injected insulin glargine in insulin-naïve type 2 diabetes patients. Results from a phase 2a Novo Nordisk–sponsored feasibility study were presented on June 13 here at the American Diabetes Association (ADA) 2017 Scientific Sessions by Leona Plum-Mörschel, PD, chief executive officer

Could a Dog Vaccine Help Save Kids With Brain Cancer?

By: Laura Goldman, Care2.com, April 17, 2017 The statistics are grim: About 60 to 70 percent of children who have glioblastoma, a form of brain cancer, do not survive more than two years. This fast-growing cancer is resistant to traditional treatments like radiation and chemotherapy. For dogs, cancer statistics are also grim. More than 6