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NIH and partners launch HIV vaccine efficacy study

The National Institutes of Health and partners have launched a large clinical trial to assess whether an experimental HIV vaccine regimen is safe and able to prevent HIV infection. The new Phase 2b proof-of-concept study, called Imbokodo, aims to enroll 2,600 HIV-negative women in sub-Saharan Africa. Of 1.8 million new HIV infections worldwide in 2016,

December 1st, 2017|Categories: Clinical Trials, HIV|Tags: , |

Researchers turn to creative approaches to battle kidney stones

Can a high-tech water bottle help reduce the recurrence of kidney stones? What about a financial incentive? Those are questions researchers funded by the National Institutes of Health will seek to answer as they begin recruiting participants for a two-year clinical trial at four sites across the country. Scientists will test whether using a smart

September 15th, 2017|Categories: Clinical Trials, Kidney Disease|Tags: |

NIH Funds SLU Research of Possible Treatment for Drug-Resistant TB

Saint Louis University is leading a multi-national clinical trial of what could become a regimen for drug resistant tuberculosis (TB) that does not require injectable medications. The project is funded by a $6.4 million task order from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). Daniel

Oral Basal Insulin Shows Promise in Type 2 Diabetes

SAN DIEGO — An oral basal insulin formulation has produced glycemic control equivalent to that of injected insulin glargine in insulin-naïve type 2 diabetes patients. Results from a phase 2a Novo Nordisk–sponsored feasibility study were presented on June 13 here at the American Diabetes Association (ADA) 2017 Scientific Sessions by Leona Plum-Mörschel, PD, chief executive officer

Could a Dog Vaccine Help Save Kids With Brain Cancer?

By: Laura Goldman, Care2.com, April 17, 2017 The statistics are grim: About 60 to 70 percent of children who have glioblastoma, a form of brain cancer, do not survive more than two years. This fast-growing cancer is resistant to traditional treatments like radiation and chemotherapy. For dogs, cancer statistics are also grim. More than 6

Stem cell transplants may induce long-term remission of multiple sclerosis

Wednesday, February 1, 2017 Encouraging results help set stage for larger studies. New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system. “...these