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Serotonin Loss May Drive Cognitive Decline

Loss of the neurotransmitter serotonin may drive cognitive decline rather than simply being a by-product of memory problems, according to new findings that have potential implications for the prevention and treatment of mild cognitive impairment (MCI). Studies have consistently shown that serotonin degeneration occurs in normal aging and Alzheimer's disease (AD), but evidence for degeneration

Increased Endometrial Cancer Rates Found in Women with High Levels of Cadmium

By Derek Thompson Researcher recommends women limit cadmium intake More than 31,000 new cases of endometrial cancer are expected to be diagnosed in 2017. Through a five-year observational study recently published in PLOS One, researchers at the University of Missouri found that women with increased levels of cadmium — a metal commonly found in foods

NCI study identifies essential genes for cancer immunotherapy

A new study identifies genes that are necessary in cancer cells for immunotherapy to work, addressing the problem of why some tumors don’t respond to immunotherapy or respond initially but then stop as tumor cells develop resistance to immunotherapy. The study, from the National Cancer Institute (NCI), was led by Nicholas Restifo, M.D., a senior

August 9th, 2017|Categories: Cancer, Disease Specific|Tags: , , |

Midlife cardiovascular risk factors may increase chances of dementia

A large, long-term study suggests that middle aged Americans who have vascular health risk factors, including diabetes, high blood pressure and smoking, have a greater chance of suffering from dementia later in life. The study, published in JAMA Neurology, was funded by the National Institutes of Health (NIH). “With an aging population, dementia is becoming

Protein-rich diet may help soothe inflamed gut

Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don’t sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues. When the balance tilts too far toward inflammation, inflammatory bowel disease can result.

Early-Life Depression Boosts Alzheimer’s Risk

Depression that starts early in life increases the risk for Alzheimer's disease (AD), as demonstrated in findings from a large, longitudinal study that is the first to report this association. This relationship has not been seen in earlier studies, Lena Johansson, PhD, Institute of Neuroscience and Physiology, Sahlgrenska Academy Center for Aging and Health, the

Immune system may mount an attack in Parkinson’s disease

A new study suggests that T cells, which help the body’s immune system recognize friend from foe, may play an important role in Parkinson’s disease (PD). The study, published in the journal Nature, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. “This collaboration between

Anxious? Cellular roots of anxiety identified

From students stressing over exams to workers facing possible layoffs, worrying about the future is a normal and universal experience. But when people’s anticipation of bad things to come starts interfering with daily life, ordinary worry can turn into an anxiety disorder. About one in four adults will struggle with anxiety at some point in

New Test Paves Way for Potential Treatments to Target Alzheimer’s

by University of Bradford A simple methodology for capturing proteins implicated in the development of Alzheimer's disease and other conditions has been developed by researchers at the University of Bradford and University of Dundee. The new methodology involves easily trapping proteins that bear a specific modification that can provide potential markers for conditions. The specific

Waterlogged brain region helps scientists gauge damage caused by Parkinson’s disease

Scientists at the University of Florida have discovered a new method of observing the brain changes caused by Parkinson’s disease, which destroys neurons important for movement. The development suggests that fluid changes in a specific brain area could provide a way to track that damage. The study, published in the journal Brain, was supported by