New Alzheimer’s Treatment Targets Identified A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets. Read more...
Landmark Alzheimer’s Drug Approval Confounds Research Community The US Food and Drug Administration (FDA) approval yesterday of the first new drug for Alzheimer’s disease in 18 years was welcomed by some people looking for hope against an intractable condition. But, for many researchers, it came as a surprise — and
Alzheimer’s Treatment Proves Effective at Preventing Inflammation, Failure of Orthopedic Implants From a simple tooth to a major knee replacement, dental and orthopedic implant surgeries to common around the globe. However, these procedures can fail due to the immune system’s response to bacteria or metal particles coming off the implants.
Draining Brain’s Debris Enhances Alzheimer’s Therapies in Mice Experimental Alzheimer’s drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations. But new research in mice has shown that some investigational Alzheimer’s therapies are more effective when paired with a treatment geared toward improving
International Alzheimer’s Clinical Trial to Test Tau Drugs A worldwide clinical trial aimed at finding treatments for Alzheimer’s disease has expanded to include investigational drugs targeting a harmful form of the brain protein tau. The trial, known as the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) and led by Washington
How Does the Immune System Keep Tabs on the Brain? Alzheimer’s disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain. There’s growing evidence that immune cells and molecules play a key role in normal brain development and function as
Novel Form of Alzheimer’s Protein Found in Spinal Fluid Indicates Stage of the Disease A novel form of an Alzheimer’s protein found in the fluid that surrounds the brain and spinal cord indicates what stage of the disease a person is in, and tracks with tangles of tau protein in
A 73-Year-Old-Woman Who Should Have Gotten Alzheimer’s, Didn’t—Revitalizing a Search for the Cure Dr. Eric Reiman can't reveal the identity of the 73-year-old woman from a rugged mountain town outside Medellin, Colombia, who arrived at Boston's Logan Airport a couple of years ago for tests at Harvard Medical School. But
Detecting Alzheimer’s Disease Before Symptoms Arise Both of Andrew Kiselica’s grandfathers developed dementia when he was in graduate school. As Kiselica was going through neuropsychology training in graduate school, he saw his mother’s father become unable to walk or speak due to severe dementia. The University of Missouri researcher said
Study Shows How to Detect Alzheimer’s Disease Before Symptoms Show A researcher at the University of Missouri has recently completed research on producing methods for defining the presymptomatic stages of Alzheimer’s disease, according to a Nov. 11 news release from the school. Read more...