Alzheimer’s/Dementia

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Antibody helps detect protein implicated in Alzheimer’s, other diseases

May lead to novel ways to diagnose, monitor brain injury by Tamara Bhandari•April 19, 2017 HUY MACH Researchers use mouse brains (above) to study ways to measure the brain protein tau, which plays a role in neurodegenerative diseases such as Alzheimer's. A team led by scientists at Washington University School of Medicine in St. Louis

Scientists discover two repurposed drugs that arrest neurodegeneration in mice

University of Cambridge April 20, 2017 A team of scientists who a few years ago identified a major pathway that leads to brain cell death in mice, have now found two drugs that block the pathway and prevent neurodegeneration. The drugs caused minimal side effects in the mice and one is already licensed for use

Antibody helps detect protein implicated in Alzheimer’s, other diseases

May lead to novel ways to diagnose, monitor brain injury by Tamara Bhandari•April 19, 2017 HUY MACH Researchers use mouse brains (above) to study ways to measure the brain protein tau, which plays a role in neurodegenerative diseases such as Alzheimer's. A team led by scientists at Washington University School of Medicine in St. Louis

$7 million aimed at illuminating the genetics of Alzheimer’s disease

Researchers working to identify genetic factors that raise, lower disease risk by Tamara Bhandari•March 13, 2017 OSCAR HARARI Studies are underway to identify the genetic networks that affect a person's risk of developing Alzheimer's disease. The researchers are aiming to find ways to predict who will develop the neurodegenerative disease, at what age and how

Jumping Genes’ May Set the Stage for Brain Cell Death in Alzheimer’s, Other Diseases

 3/10/17 by Duke University Alzheimer's disease causes neurons in the brain to stop working, lose connections with other neurons and die. Duke University researchers have identified a molecular mechanism that may be responsible for setting the damage in motion. Alzheimer's disease causes neurons in the brain to stop working, lose connections with other neurons and

Alzheimer’s Staggering $259B Cost Could Break Medicare

Mar. 7, 2017 Bruce Japsen ,  CONTRIBUTOR The cost of providing care for Americans with Alzheimer’s disease has hit $259 billion–more than a quarter of a trillion dollars–as costs mount to treat more aging baby boomers entering long-term care facilities, according to a new report. The annual cost estimate for the deadly disease from the

Landmark Alzheimer’s prevention trial to evaluate third drug

Effort to study drug's ability to prevent, delay the disease By Tamara Bhandari December 19, 2016 Washington University School of Medicine's Randall J. Bateman, MD, talks with DIAN-TU trial participant Natalie Shriver, of Omaha, about a study to test drugs that may prevent or delay Alzheimer's disease. (Photo: Robert Boston/Washington University School of Medicine) An

Earlier Alzheimer’s diagnosis may be possible with new imaging compound

New tool detects Alzheimer’s protein, may help identify brain changes, assess treatment effects By Tamara Bhandari November 2, 2016 Researchers at Washington University School of Medicine in St. Louis have developed a chemical compound that detects the Alzheimer’s protein amyloid beta better than current FDA-approved agents. The compound potentially may be used in brain scans to

November 2nd, 2016|Categories: Alzheimer's/Dementia, Around The State|

From labs to lives: Self-replicating cells help treat neuro disorders

July 27, 2016 Scientists estimate that human bodies contain anywhere from 75 to 100 trillion cells. And of these cells, there are hundreds of different types. Yet, one cell type in particular has captured the fascination of assistant professor David Brafman: the human pluripotent stem cell (hPSC).Assistant professor David Brafman mentoring biomedical engineering junior Lexi

$4 million grant expands major study to find Alzheimer’s prevention treatments

Investigators will accelerate drug testing, develop new diagnostic measures by Tamara Bhandari • June 21, 2016 JUDY MARTIN FINCH Dean DeMoe, a participant in the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) study at Washington University, receives AV1451 — a radiopharmaceutical — from imaging technologist Holly Karsch. AV1451 binds to tau protein in the brain. Washington University