New Alzheimer’s Prevention Trial in Young People Washington University School of Medicine in St. Louis is launching an international clinical trial aimed at preventing Alzheimer’s disease in people genetically destined to develop the illness at a young age. Unlike most other Alzheimer’s prevention trials, this one will enroll people before
Scientists Reveal How Alzheimer’s Progresses in the Brain In people with Alzheimer’s, plaques of a misfolded protein called beta-amyloid, and fibrous tangles of another misfolded protein called tau, accumulate in the brain and kill nerve cells. This gradual loss of nerve cells causes shrinkage of the brain and eventually interferes
New Alzheimer’s Treatment Targets Identified A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets. Read more...
Landmark Alzheimer’s Drug Approval Confounds Research Community The US Food and Drug Administration (FDA) approval yesterday of the first new drug for Alzheimer’s disease in 18 years was welcomed by some people looking for hope against an intractable condition. But, for many researchers, it came as a surprise — and
Alzheimer’s Treatment Proves Effective at Preventing Inflammation, Failure of Orthopedic Implants From a simple tooth to a major knee replacement, dental and orthopedic implant surgeries to common around the globe. However, these procedures can fail due to the immune system’s response to bacteria or metal particles coming off the implants.
Draining Brain’s Debris Enhances Alzheimer’s Therapies in Mice Experimental Alzheimer’s drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations. But new research in mice has shown that some investigational Alzheimer’s therapies are more effective when paired with a treatment geared toward improving
International Alzheimer’s Clinical Trial to Test Tau Drugs A worldwide clinical trial aimed at finding treatments for Alzheimer’s disease has expanded to include investigational drugs targeting a harmful form of the brain protein tau. The trial, known as the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) and led by Washington