New Alzheimer’s Treatment Targets Identified

New Alzheimer’s Treatment Targets Identified A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer’s disease, as well as existing drugs that have therapeutic potential against these targets. Read more...

Landmark Alzheimer’s Drug Approval Confounds Research Community

Landmark Alzheimer’s Drug Approval Confounds Research Community The US Food and Drug Administration (FDA) approval yesterday of the first new drug for Alzheimer’s disease in 18 years was welcomed by some people looking for hope against an intractable condition. But, for many researchers, it came as a surprise — and

Draining Brain’s Debris Enhances Alzheimer’s Therapies in Mice

Draining Brain’s Debris Enhances Alzheimer’s Therapies in Mice Experimental Alzheimer’s drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations. But new research in mice has shown that some investigational Alzheimer’s therapies are more effective when paired with a treatment geared toward improving

International Alzheimer’s Clinical Trial to Test Tau Drugs

International Alzheimer’s Clinical Trial to Test Tau Drugs A worldwide clinical trial aimed at finding treatments for Alzheimer’s disease has expanded to include investigational drugs targeting a harmful form of the brain protein tau. The trial, known as the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) and led by Washington

How Does the Immune System Keep Tabs on the Brain?

How Does the Immune System Keep Tabs on the Brain? Alzheimer’s disease, multiple sclerosis, autism, schizophrenia and many other neurological and psychiatric conditions have been linked to inflammation in the brain. There’s growing evidence that immune cells and molecules play a key role in normal brain development and function as

Detecting Alzheimer’s Disease Before Symptoms Arise

Detecting Alzheimer’s Disease Before Symptoms Arise Both of Andrew Kiselica’s grandfathers developed dementia when he was in graduate school. As Kiselica was going through neuropsychology training in graduate school, he saw his mother’s father become unable to walk or speak due to severe dementia. The University of Missouri researcher said