Autism

Late-breaking Mutations May Play an Important Role in Autism

by Boston's Children's Hospital A study of nearly 6,000 families, combining three genetic sequencing technologies, finds that mutations that occur after conception play an important role in autism. A team led by investigators at Boston Children's Hospital and the Broad Institute of MIT and Harvard reports the findings today in Nature Neuroscience. Over the past decade,

July 24th, 2017|Categories: Autism, Disease Specific|Tags: , , |

In autism, genes drive early eye gaze abnormalities

Twin study reveals strong genetic influences on how infants visually explore social world New research has uncovered compelling evidence that genetics plays a major role in how children look at the world and whether they have a preference for gazing at people’s eyes and faces or at objects. The discovery by researchers at Washington University

Brain Patterns at 6 Months Predict Autism in High-Risk Infants

Magnetic resonance imaging (MRI) studies of brain connectivity in 6-month-old infants at high risk for autism successfully identified 9 of 11 babies who went on to be diagnosed with the disorder at 24 months of age, according to findings published online today in Science Translational Medicine. Moreover, the imaging data correctly categorized all 48 of

June 15th, 2017|Categories: Autism|Tags: , , , , , |

Researchers connect molecular function to high blood pressure, diseases

By Beth Miller March 1, 2017 Jianmin Cui’s lab investigated mechanisms of the an important ion channel called the BK channel, which is associated with high blood pressure, autism and movement disorders. By changing one small portion of a stimulus that influences part of one molecule’s function, engineers and researchers at Washington University in St. Louis

Unraveling autism

A multifaceted approach aims to detect, treat and even reverse the disorder. BY REBECCA BOYLE, January 3, 2017 Washington University in St. Louis - Like many patients visiting a doctor’s office, Kim Sebenoler started out her appointment by heading to the nearest restroom to give a urine sample. But her visit to the lab of

Discovery of a ‘Neuronal Big Bang’

Mon, 03/07/2016 - 11:07am University of Geneva This is an expression of all the genes of a neuron during the first hours after its birth. Each circle represents a development stage (6h, 12h, 24h), and the colored points within each circle represent the level of gene expression. (Credit: Jabaudon Lab/ UNIGE)Our brain is home to different

Loss of support cells in brain may inhibit neuronal development

October 6, 2015 By Jim Dryden Washington University School of Medicine researchers Courtney Sobieski (left) and Steven Mennerick, PhD, found, in culture, that without cells called astrocytes, neurons send signals to one another more slowly. That slowdown could interfere with neuronal development and contribute to conditions linked to communication between neurons. Shedding light on possible

As CIRM opens world’s largest stem cell bank, scientists ready their research

Sep 1, 2015 A $32 million public-private bank — where California researchers collect stem cells and scientists from around the world can make withdrawals — officially opened Tuesday with the aim of accelerating the use of engineered stem cells to tackle a wide range of diseases. The bank, funded by the California Institute for Regenerative

Receptors in brain linked to schizophrenia, autism

Mice lacking a set of receptors in one type of neuron in the brain developed compulsive, anti-social behaviors, Salk scientists found August 11, 2015 LA JOLLA–The loss of a critical receptor in a special class of inhibitory neurons in the brain may be responsible for neurodevelopmental disorders including autism and schizophrenia, according to new research