Blood Disorders

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Scientists find culprit responsible for calcified blood vessels in kidney disease

Stem cell finding informs research to prevent hardening of arteries By Julia Evangelou Strait September 8, 2016 A new study indicates that stem cells called Gli1 cells (shown in red) are responsible for depositing calcium in the arteries, increasing the risk of atherosclerosis. Over time, the condition can lead to cardiovascular disease and is especially

Blood-forming stem cells likely hold the key to curing many types of disease

Science Friday July 20, 2016 · 7:45 AM EDT By Adam Wernick Researchers at Stanford are reviving a technique that can use uncontaminated, blood-forming stem cells to treat a patient with cancer, autoimmune deficiency and other diseases. Beginning in the 1960s, hematopoietic, or blood-forming, stem cells became the basis for bone marrow transplants used to treat cancer patients. Then, in the 1980s and

Genetic error that increases risk of aortic rupture identified

Study sheds light on unexplained enlargement, weakening of aorta By Julia Evangelou Strait July 18, 2016 In young people, aortic aneurysms are most often caused by an inherited condition,such as Marfan syndrome. Standard genetic tests often pinpoint the reason for inheritedaortic disease, but some cases remain medical mysteries. A new study adds lysyl oxidaseto the

Body’s Own Gene Editing System Generates Leukemia Stem Cells

Inhibiting the editing enzyme may provide a new therapeutic approach for blood cancers June 09, 2016  |  Heather Buschman, PhD, UCSan Diego Health Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and

June 9th, 2016|Categories: Blood Disorders, Cancer|Tags: , , |

Making bone marrow transplants safer

New approach would use antibodies rather than radiation and chemotherapy June 7, 2016 | Editor's Pick Popular  By Hannah L. Robbins, Harvard Stem Cell Institute B.D. Colen/Harvard Stem Cell Institute Communications Rahul Palchaudhuri (left), postdoctoral fellow, and David Scadden, co-director of the Harvard Stem Cell Institute, look at real-time images of blood stem cells settling

‘Step forward’ in battle against blood disorders

Belfast Telegraph April 8, 2016 British scientists have taken a first step towards mass-producing platelets - tiny cell fragments that play a vital role in blood clotting - tailored to individual patients. The team, including researchers from the NHS organisation responsible for blood transfusions, transformed stem cells into the large bone marrow cells called megakaryocytes

Mount Sinai Researchers Report Insights into Blood Stem Cells from Engineered Stem Cells

Building upon previous work, researchers at the Icahn School of Medicine at Mount Sinai have identified a precursor cell in the placenta and embryo of mice that can be matured in the lab to make hematopoietic stem/progenitor cells NEW YORK, NY (PRWEB) MARCH 08, 2016 Building upon previous work, researchers at the Icahn School of

Researchers Identify Mechanism that Impairs Blood Flow with Aging

New findings could lead to treatments for age-related vascular disease September 8, 2015 With the world’s elderly population expected to double by 2050, understanding how aging affects the body is an important focus for researchers globally. Cardiovascular disease, the No. 1 cause of death worldwide, often is associated with aging arteries that restrict blood flow.

SLU Researcher Opens Next Chapter on Blood-Clotting Mysteries

Grant to SLU from American Heart Association Builds on Breakthrough Research August 31, 2015 Saint Louis University Carrie Bebermeyer ST. LOUIS — Last summer, SLU scientists made a breakthrough discovery about the way in which blood clots. Through X-ray crystallography, they solved the molecular structure of prothrombin, an important blood-clotting protein, revealing an unexpected, flexible role for a

Compound Found in Red Wine Causes Conflicting Changes in Dogs’ Immune Systems

Resveratrol research in dogs could eventually lead to treatments in humans Aug. 24, 2015 Nathan Hurst   COLUMBIA, Mo. – Resveratrol, a compound found commonly in grape skins and red wine, has been shown to have several potentially beneficial effects on health, including cardiovascular health, stroke prevention and cancer treatments. However, scientists do not yet