New Cancer Treatments May be on the Horizon — Thanks to mRNA Vaccines The COVID-19 pandemic brought mRNA vaccines into the limelight. But the technology may also prove to be a powerful weapon against hard-to-treat cancers. Read more...
Death Rates are Declining for Many Common Cancers in the U.S., Report Finds The new report — released by the American Cancer Society, the National Cancer Institute, the Centers for Disease Control and Prevention, and other collaborators — found that between 2014 and 2018, death rates dropped for 11 out
Cell-Based Immunotherapy Shows Promise Against Melanoma An immunotherapy based on supercharging the immune system’s natural killer cells has been effective in treating patients with recurrent leukemia and other difficult to treat blood cancers. Now, researchers at Washington University School of Medicine in St. Louis have shown in preclinical studies conducted
Newly Approved Drug Effective Against Lung Cancer Caused by Genetic Mutation The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed to
Understanding How Cancer Can Relapse In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one of these mutations — oncogenic RAS or RASV12 —
Zika Virus Helps Destroy Deadly Brain Cancer in Mice The Zika virus that ravaged the Americas, leaving many babies with permanent brain damage, may have a silver lining. The virus can activate immune cells to destroy an aggressive brain cancer in mice, giving a powerful boost to an immunotherapy drug
Developing a Targeted Delivery System to Treat Cancer In the ongoing battle to find ways to treat cancer, a team at the University of Missouri is addressing the problem from multiple angles, but with a precision approach. Cancer patients are often given chemotherapy, cancer-fighting drugs that kill cancerous cells and
Bristol Myers Squibb Wins First CAR-T Therapy Approval in Multiple Myeloma The FDA has approved a Bristol Myers Squibb cell therapy made by engineering a patient’s immune cells to target a cancer protein called BCMA. The regulatory decision for Abecma in multiple myeloma gives BMS its second approved CAR-T therapy.
Promising Role for Whole Genome Sequencing in Guiding Blood Cancer Treatment For certain blood cancers, such as acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), deciding whether patients need an aggressive treatment typically hinges on a set of lab tests to identify genetic changes. Some of these tests rely on
Salk Team Reveals Never-Before-Seen Antibody Binding, Informing Both Liver Cancer and Antibody Design
Salk Team Reveals Never-Before-Seen Antibody Binding, Informing Both Liver Cancer and Antibody Design In structural biology, some molecules are so unusual they can only be captured with a unique set of tools. That’s precisely how a multi-institutional research team led by Salk scientists defined how antibodies can recognize a compound