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Scientists ID source of damaging inflammation after heart attack

Scientists have zeroed in on a culprit that spurs damaging inflammation in the heart following a heart attack. The guilty party is a type of immune cell that tries to heal the injured heart but instead triggers inflammation that leads to even more damage. Further, the researchers have found that an already approved drug effectively

MU School of Medicine researcher uncovers clue to as to how disease processes develop

A new study could have major implications for our understanding of disease processes for conditions such as autoimmunity, atherosclerosis and heart failure, potentially leading to better prevention and treatment. Dr. Edward T.H. Yeh, chairman of the Department of Medicine and director of the Center for Precision Medicine at the University of Missouri School of Medicine, has been leading a team of

SLU Researchers Discover Structure of Protein Associated with Inflammation, Parkinson’s

In a recent paper published in Nature Communications, Saint Louis University scientists report that they have determined the structure of a key protein that is involved in the body’s inflammatory response. This finding opens the door to developing new treatments for a wide range of illnesses, from heart disease, diabetes and cancer to neurodegenerative disorders, including

Coronary Calcium Helps Stratify 10-Year Cardiac Risk in Diabetes

IRVINE, CA — Coronary artery calcium (CAC) scores may be better at predicting the risk of a cardiovascular disease (CVD) event in patients with type 2 diabetes than traditional scores such as Framingham, even in those who've had diabetes for 10 years, researchers report[1]. This conclusion is based on a new analysis of participants in

More Evidence Physical Activity Reduces Cardiovascular Risk

OXFORD, UK — A study of close to 500,000 people without cardiovascular disease (CVD) at baseline showed that total physical activity related to work, recreation, or utilitarian needs such as walking to do errands was associated with a lower short-term risk of developing CVD.[1] The researchers found that there is a "clearly positive . . . dose-response relationship between

December 3rd, 2017|Categories: Disease Specific, Heart Disease|Tags: , , |

Immune Cells Mistake Heart Attacks for Viral Infections

A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic strategies for heart disease The team, which also includes researchers from the Center for Systems

Blood Cancer Gene Could be Key to Preventing Heart Failure

A new study, published today in Circulation, shows that the gene Runx1 increases in damaged heart muscle after a heart attack. An international collaboration led by researchers from the University of Glasgow, found that mice with a limited capacity to increase Runx1 gene activation were protected against the adverse changes that lead to heart failure. Coronary

Tension Makes the Heart Grow Stronger

By taking videos of a tiny beating zebrafish heart as it reconstructs its covering in a petri dish, scientists have captured unexpected dynamics of cells involved in tissue regeneration. They found that the depleted heart tissue regenerates itself in a wave, led by a front of fast-moving, supersized cells and trailed by smaller cells that

High Salt Intake Linked to Increased Heart-Failure Risk

BARCELONA, SPAIN — High daily salt intake is associated with a substantial increase in an individual's risk of developing heart failure, independent of other risk factors, suggests one of the largest studies to accurately measure salt consumption[1]. The analysis of more than 4500 individuals, presented here at the European Society of Cardiology (ESC) 2017 Congress, indicated

September 12th, 2017|Categories: Disease Specific, Heart Disease|Tags: , |