Inflammatory Bowel Disease (IBD)

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Protein-rich diet may help soothe inflamed gut

Immune cells patrol the gut to ensure that harmful microbes hidden in the food we eat don’t sneak into the body. Cells that are capable of triggering inflammation are balanced by cells that promote tolerance, protecting the body without damaging sensitive tissues. When the balance tilts too far toward inflammation, inflammatory bowel disease can result.

Lab-Grown Human ‘Mini Lungs’ Successfully Engraft in Mice, a Respiratory Research Breakthrough

Shantell M. Kirkendoll November 07, 2016 6:00 AM Scientists can now grow 3-D models of various organs from stem cells, creating new ways to study disease. More than a year ago, scientists made studying lung cells in a petri dish appear old-fashioned. A team led by University of Michigan Medical School researchers coaxed stem cells to

Gut microbes’ metabolite dampens proliferation of intestinal stem cells

Finding may provide clues to limitations of potential IBD treatment By  Tamara Bhandari June 2, 2016 Intestinal stem cells are sequestered in pockets in the lining of the intestine to avoid contact with a metabolite produced by beneficial microbes in the gut. That metabolite — butyrate — restricts the proliferation of stem cells, shown here in

UTSW Researchers Find Molecule Able to Accelerate Tissue Regeneration Upon Injury

July 20, 2015 Patricia Silva - A study recently published in the renowned journal Science revealed a molecule able to accelerate tissue regeneration after bone marrow transplantation and other tissue injuries in mice. The study is entitled “Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration” and was led by researchers at the University of

‘Bio-Artificial’ Intestine Offers New Hope for Serious Bowel Diseases

Digestive Disease Week (DDW) 2015 Luca Cicalese, MD - June 26, 2015 What if people with seriously diseased or damaged intestines could use their own stem cells to grow new "bio-artificial" intestinal tissue to replace parts of their bowels? It certainly would be a life-changing and life-saving discovery for countless children who are born with congenital conditions, such as

NIH researchers reveal link between powerful gene regulatory elements and autoimmune diseases

Findings point to potential drug targets Tuesday, February 17, 2015 Investigators with the National Institutes of Health have discovered the genomic switches of a blood cell key to regulating the human immune system. The findings, published in Nature today, open the door to new research and development in drugs and personalized medicine to help those

Stem Cell Therapies for Celiac Disease and IBD Now Offered in the United States

PRWebb, by Staff ~ January 21, 2014 Regenerative Medicine Solutions (RMS), a global provider of stem cell treatments for degenerative diseases, is now offering Regenerative ColoTherapy (RCT), a proprietary stem cell treatment for people suffering with celiac and inflammatory bowel disease (IBD). Crohn’s disease and ulcerative colitis (UC) are two of the most notable conditions

Research Supports Promise of Cell Therapy for Bowel Disease

Feb. 28, 2013 - by Karen Richardson WINSTON-SALEM, N.C. - Researchers at Wake Forest Baptist Medical Center and colleagues have identified a special population of adult stem cells in bone marrow that have the natural ability to migrate to the intestine and produce intestinal cells, suggesting their potential to restore healthy tissue in patients with