Kidney Disease

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Yale scientists develop novel technique for kidney research

By Ziba Kashef August 24, 2015 One in four patients treated with the widely used anti-cancer drug cisplatin develop chronic kidney disease. To better understand how the treatment leads to kidney damage, and possibly prevent it, a team of researchers at Yale School of Medicine developed a new 3D-imaging technique to peer deep into these

UTSW Researchers Find Molecule Able to Accelerate Tissue Regeneration Upon Injury

July 20, 2015 Patricia Silva - A study recently published in the renowned journal Science revealed a molecule able to accelerate tissue regeneration after bone marrow transplantation and other tissue injuries in mice. The study is entitled “Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration” and was led by researchers at the University of

Organ transplant rejection may not be permanent

Organ transplant rejection in previously tolerant hosts does not lead to permanent immune memory, mouse study shows July 7, 2015 Rejection of transplanted organs in hosts that were previously tolerant may not be permanent, report scientists from the University of Chicago. Using a mouse model of cardiac transplantation, they found that immune tolerance can spontaneously

Washington University develops genetic test for inherited kidney diseases

March 26, 2015 By Michael C. Purdy and Gaia Remerowski GPS A new test from Washington University’s Genomic Pathology Services will help physicians quickly zero in on genetic mutations that may be contributing to kidney disease. Many kidney disorders are difficult to diagnose. To address this problem, scientists and clinicians have developed a diagnostic test

Doctors getting clearer picture of how to slow or stop kidney disease in children

BY ALAN BAVLEY THE KANSAS CITY STAR 03/19/2015   Marley Martinac, 2, is a kidney patient at Children’s Mercy Hospital, but mom Katie Martinac says the girl is as spunky as ever. Marley used her Doc McStuffins mobile cart to give her dog, Kamo, a checkup at the family’s home in Bates City. KEITH MYERS THE KANSAS

Kidney Cancer Detected Early With Urine Test

By Jim Dryden When kidney cancer is diagnosed early — before it spreads — 80 percent of patients survive. But early diagnosis is a challenge. Now, Washington University School of Medicine researchers Evan D. Kharasch, MD, PhD (left) and Jeremiah J. Morrissey, PhD, have developed a noninvasive method to screen for kidney cancer by measuring

Researchers Generate Kidney Tubular Cells from Stem Cells

ScienceDaily, by Staff Dec. 19, 2013 — Investigators have discovered a cocktail of chemicals which, when added to stem cells in a precise order, turns on genes found in kidney cells in the same order that they turn on during embryonic kidney development. The kidney cells continued to behave like kidney cells when transplanted into

Researchers investigate use of pig kidneys for human transplant

According to the National Kidney Foundation, around 96,645 patients in the US are awaiting kidney transplants as a result of kidney failure. However, less than 17,000 kidney transplantations are carried out each year due to a shortage of donors. But a new option could soon be available - in the form of pig kidneys. Researchers

‘Mini-Kidney’ Structures Generated from Human Stem Cells for First Time

ScienceDaily, by Staff ~ November 17, 2013 Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology. Now, a team of researchers led by scientists at the Salk Institute for

Stem cells in urine easy to isolate and have potential for numerous therapies

03 Aug 2013 - 0:00 PDT Could harvesting stem cells for therapy one day be as simple as asking patients for a urine sample? Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have identified stem cells in urine that can be directed to become multiple cell types. "These cells can be obtained through