Liver Disease

Home/Disease Specific/Liver Disease

Tonsil stem cells could someday help repair liver damage without surgery

Medical News Today, Source: American Chemical Society ~ October 17, 2014 The liver provides critical functions, such as ridding the body of toxins. Its failure can be deadly, and there are few options for fixing it. But scientists now report in the journal ACS Applied Materials & Interfaces a way to potentially inject stem cells

Tonsil stem cells could someday help repair liver damage without surgery

R&D, Source: American Chemical Society ~ September 24, 2014 The liver provides critical functions, such as ridding the body of toxins. Its failure can be deadly, and there are few options for fixing it. But scientists now report in the journal ACS Applied Materials & Interfaces a way to potentially inject stem cells from tonsils,

Fatty liver disease prevented in mice

June 2, 2014 By Julia Evangelou Strait, Senior Medical Science Writer, Washington University BRIAN J. DEBOSCH A transporter called GLUT8 (green) is in the outer membrane of liver cells. In mice, blocking GLUT8 stops fructose from entering the liver and protects against nonalcoholic fatty liver disease. The liver cell nuclei are shown in blue. Studying mice,

SLU Researchers to Study Alpha-1 Liver Disease in adults

The study aims to understand the natural history and progression of the disease ST. LOUIS - Researchers at Saint Louis University will study alpha-1 antitrypsin deficiency in adults, an inherited disease that can cause liver damage, to answer various questions that could lead to effective methods of treatment. Jeffrey Teckman, M.D., is a professor of

Erasing a Genetic Mutation

Bioscience Technology, Source: Massachusetts Institute of Technology ~ March 31, 2014 Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings, described in the March 30 issue of Nature Biotechnology, offer the first evidence that this gene-editing technique,

Erasing a Genetic Mutation

Monday, 3/31/2014 Bioscience Technology Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings, described in the March 30 issue of Nature Biotechnology, offer the first evidence that this gene-editing technique, known as CRISPR, can reverse disease symptoms

Scientists transform skin cells into functioning liver cells

Medical Xpress, by Staff ~ February 23, 2014 The power of regenerative medicine now allows scientists to transform skin cells into cells that closely resemble heart cells, pancreas cells and even neurons. However, a method to generate cells that are fully mature—a crucial prerequisite for life-saving therapies—has proven far more difficult. But now, scientists at

New tool for discovering how gene circuits operate

Medical News Today, by Staff ~ January 13, 2014 A fast and comprehensive method for determining the function of genes could greatly improve our understanding of a wide range of diseases and conditions, such as heart disease, liver disease and cancer. The method uses stem cells with a single set of chromosomes, instead of the

One Step Closer to Artificial Livers

Mon, 2013-06-03 10:16 - Source: MIT, reprinted by BioScience Technology MIT researchers have generated mature liver cells from induced pluripotent stem cells. In this image, the cell nuclei are stained blue. The green stain identifies liver cells, and the red stain identifies cells that are actively dividing. (Source: MIT/Nature Chemical Biology, 2013/Shan et al.) Prometheus,