Parkinson’s Disease

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Scientists discover two repurposed drugs that arrest neurodegeneration in mice

University of Cambridge April 20, 2017 A team of scientists who a few years ago identified a major pathway that leads to brain cell death in mice, have now found two drugs that block the pathway and prevent neurodegeneration. The drugs caused minimal side effects in the mice and one is already licensed for use

Your brain cells could be reprogrammed to fight Parkinson’s Disease

IN BRIEF Researchers have reprogrammed existing brain cells in mice into dopamine neurons to reduce their symptoms of Parkinson's disease. This novel approach could be used to treat Parkinson's disease with stem cells which are not transplanted, but induced from patients' own brain cells. SUPPORT CELLS TURNED SUPER CELLS Parkinson’s disease is one of the

Surprising culprit in nerve cell damage identified

Findings suggest ways to block nerve cell damage in neurodegenerative diseases By Julia Evangelou Strait March 22, 2017 Nerve axons (left) serve as the electrical wiring of the nervous system. Scientists have implicated a specific molecule in triggering a self-destruct program in axons that leads to their degeneration (right). Since axonal degeneration is a common thread

Steroid originally discovered in the dogfish shark attacks Parkinson’s-related toxin in animal model

Credit: Doug Costa, NOAA/SBNMS MEDIA CONTACT: Karen Teber WASHINGTON (January 16, 2017) — A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson’s disease. The clustering of this protein, alpha-synuclein (α-synuclein), is the

Breakthrough in the production of dopamine neurons for Parkinson’s disease

Published: 29/10/2016 - Lund University, Sweden The first transplantation of stem cells in patients with Parkinson's disease is almost within reach. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients. - In our preclinical assessments of stem

Making Every Cell Matter

October 31, 2016 A new method for encapsulating single cells within tunable microgels could boost efficacy of cell-based therapies and tissue engineering (CAMBRIDGE, Massachusetts) – Alginate hydrogels – which are derived from the polysaccharide found in brown seaweed – have emerged as an effective material for manipulating cells and tissues due to their biocompatibility and

Scientists develop a new approach for Parkinson’s disease therapy

Wednesday, August 3, 2016 - 00:19   SPECIAL TO HNN PROVIDED BY MARSHALL UNIVERSITY Last year, Dr. Elmer Price, a professor of biological sciences at Marshall University, was awarded a three-year, $350,000 research grant from the National Science Foundation. The grant funds his research into understanding neurogenesis, the process adult brains use to generate new

Michael J. Fox Foundation supports two stem cell research projects for Parkinson’s

Harvard Teaching Hospitals funded to develop dopamine neuron replacement treatment -- Parkinson's Progression Markers Initiative making iPSCs available to broad research community -- Dopamine neurons engineered from iPSCs may hold utility as therapeutics and research tools May 25, 2016, 10:00 ET from The Michael J. Fox Foundation NEW YORK, May 25, 2016 /PRNewswire-USNewswire/ -- The

University Develops First Diagnostic Blood Test for Parkinson’s

Thu, 04/21/2016 - 12:22pm Greg Watry, Digital Reporter, R&D The Parkinson’s Disease Foundation estimates that between 7 and 10 million people globally are living with Parkinson’s disease. In the United States alone, the direct and indirect costs of the disease are estimated at $25 billion per year. Currently, no specific diagnostic test is available for