Parkinson’s Disease

Home/Disease Specific/Parkinson's Disease

Immune system may mount an attack in Parkinson’s disease

A new study suggests that T cells, which help the body’s immune system recognize friend from foe, may play an important role in Parkinson’s disease (PD). The study, published in the journal Nature, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. “This collaboration between

Waterlogged brain region helps scientists gauge damage caused by Parkinson’s disease

Scientists at the University of Florida have discovered a new method of observing the brain changes caused by Parkinson’s disease, which destroys neurons important for movement. The development suggests that fluid changes in a specific brain area could provide a way to track that damage. The study, published in the journal Brain, was supported by

Immune response linked to Parkinson’s disease

Parkinson’s disease is a degenerative brain disorder that develops when nerve cells in the brain become impaired and eventually die. As these brain cells die, people with Parkinson’s disease may start experiencing involuntary shaking, muscle stiffness, slowed movements, problems with balance, and other symptoms. At first, only a tremor in one hand may be noticeable.

Scientists discover two repurposed drugs that arrest neurodegeneration in mice

University of Cambridge April 20, 2017 A team of scientists who a few years ago identified a major pathway that leads to brain cell death in mice, have now found two drugs that block the pathway and prevent neurodegeneration. The drugs caused minimal side effects in the mice and one is already licensed for use

Your brain cells could be reprogrammed to fight Parkinson’s Disease

IN BRIEF Researchers have reprogrammed existing brain cells in mice into dopamine neurons to reduce their symptoms of Parkinson's disease. This novel approach could be used to treat Parkinson's disease with stem cells which are not transplanted, but induced from patients' own brain cells. SUPPORT CELLS TURNED SUPER CELLS Parkinson’s disease is one of the

Surprising culprit in nerve cell damage identified

Findings suggest ways to block nerve cell damage in neurodegenerative diseases By Julia Evangelou Strait March 22, 2017 Nerve axons (left) serve as the electrical wiring of the nervous system. Scientists have implicated a specific molecule in triggering a self-destruct program in axons that leads to their degeneration (right). Since axonal degeneration is a common thread

Steroid originally discovered in the dogfish shark attacks Parkinson’s-related toxin in animal model

Credit: Doug Costa, NOAA/SBNMS MEDIA CONTACT: Karen Teber WASHINGTON (January 16, 2017) — A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson’s disease. The clustering of this protein, alpha-synuclein (α-synuclein), is the

Breakthrough in the production of dopamine neurons for Parkinson’s disease

Published: 29/10/2016 - Lund University, Sweden The first transplantation of stem cells in patients with Parkinson's disease is almost within reach. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients. - In our preclinical assessments of stem

Making Every Cell Matter

October 31, 2016 A new method for encapsulating single cells within tunable microgels could boost efficacy of cell-based therapies and tissue engineering (CAMBRIDGE, Massachusetts) – Alginate hydrogels – which are derived from the polysaccharide found in brown seaweed – have emerged as an effective material for manipulating cells and tissues due to their biocompatibility and