Understanding How Cancer Can Relapse

Understanding How Cancer Can Relapse In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options. Now, scientists at the University of Missouri and Yale University have discovered that one of these mutations — oncogenic RAS or RASV12 —

Scientists Find Genetic Link to Clogged Arteries

Scientists Find Genetic Link to Clogged Arteries High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke. But now, scientists at Washington University School of Medicine in St. Louis have identified a gene that likely plays

Zika Virus Helps Destroy Deadly Brain Cancer in Mice

Zika Virus Helps Destroy Deadly Brain Cancer in Mice The Zika virus that ravaged the Americas, leaving many babies with permanent brain damage, may have a silver lining. The virus can activate immune cells to destroy an aggressive brain cancer in mice, giving a powerful boost to an immunotherapy drug

International Alzheimer’s Clinical Trial to Test Tau Drugs

International Alzheimer’s Clinical Trial to Test Tau Drugs A worldwide clinical trial aimed at finding treatments for Alzheimer’s disease has expanded to include investigational drugs targeting a harmful form of the brain protein tau. The trial, known as the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU) and led by Washington

Developing a Targeted Delivery System to Treat Cancer

Developing a Targeted Delivery System to Treat Cancer In the ongoing battle to find ways to treat cancer, a team at the University of Missouri is addressing the problem from multiple angles, but with a precision approach. Cancer patients are often given chemotherapy, cancer-fighting drugs that kill cancerous cells and

A Niche for the Eye

A Niche for the Eye What if the degenerative eye conditions that lead to glaucoma, corneal dystrophy, and cataracts could be detected and treated before vision is impaired? Recent findings from the lab of Investigator Ting Xie, PhD, at the Stowers Institute for Medical Research point to the ciliary body

CRISPR-Based Anti-Viral Therapy Could One Day Foil the Flu—and COVID-19

CRISPR-Based Anti-Viral Therapy Could One Day Foil the Flu—and COVID-19 CRISPR gene-editing technology has tremendous potential for making non-heritable DNA changes that can treat or even cure a wide range of devastating disorders, from HIV to muscular dystrophy Now, a recent animal study shows that another CRISPR system—targeting viral RNA