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CRISPR technology adapted to edit RNA

Genome editing is a powerful technique that has the potential to correct human diseases caused by genetic errors. Many human diseases have been linked to an error, or mutation, in a gene’s DNA sequence. A common type of mutation is a single DNA nucleotide change, called a point mutation. Depending on where it’s located, a

November 22nd, 2017|Categories: Uncategorized|

Postconception Genetic Mutations Contribute to Autism Risk

Mutations that occur after conception may play an important role in autism spectrum disorder (ASD), according to a study of nearly 6000 families that combined three genetic sequencing techniques. "Our study has uncovered new mutations in ASD, as well as provided additional evidence for some genes that have been previously reported in ASD," first author,

August 4th, 2017|Categories: Uncategorized|

FDA Approves Novel Leukemia Treatment that Could Be First U.S. Gene Therapy

By Linda Johnson, Associated Press A treatment for a common childhood blood cancer could become the first gene therapy available in the U.S. A Food and Drug Administration advisory panel voted 10-0 on Wednesday in favor of the leukemia treatment developed by the University of Pennsylvania and Novartis Corp. The FDA usually follows recommendations from

July 19th, 2017|Categories: Cancer, Uncategorized|Tags: , , |

Oral Basal Insulin Shows Promise in Type 2 Diabetes

SAN DIEGO — An oral basal insulin formulation has produced glycemic control equivalent to that of injected insulin glargine in insulin-naïve type 2 diabetes patients. Results from a phase 2a Novo Nordisk–sponsored feasibility study were presented on June 13 here at the American Diabetes Association (ADA) 2017 Scientific Sessions by Leona Plum-Mörschel, PD, chief executive officer

New findings shed light on fundamental process of DNA repair

September 8, 2015 Inside the trillions of cells that make up the human body, things are rarely silent. Molecules are constantly being made, moved, and modified — and during these processes, mistakes are sometimes made. Strands of DNA, for instance, can break for any number of reasons, such as exposure to UV radiation, or mechanical

Scientists generate pluripotent stem cells with more stable genomes

August 28, 2015 at 1:48 AM Damaged tissue, such as pancreas, heart, and neuronal tissue, which is regenerated to treat cardiovascular diseases, diabetes, or neurodegenerative diseases. This is one of the ambitious scenarios to which regenerative medicine aspires and that is being announced as one of the great promises of twenty-first century biomedicine for the

August 28th, 2015|Categories: Uncategorized|Tags: , , |

Elastic Drug Delivery Technology Releases Drugs When Stretched

August 11, 2015 - Zhen Gu  |  Mick Kulikowski   Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a drug delivery technology that consists of an elastic patch that can be applied to the skin and will release drugs whenever the patch is stretched. For example, if applied

Regenerative medicine: Injectable stem cell incubator

5/29/2015 From: Kate McAlpine, Michigan Engineering Some tissue damage is too extensive for the body to heal well, such as a bad slipped disc or the muscle death that follows a heart attack, so researchers are looking for ways to bridge the gaps. The most promising avenue is stem cell therapy, but these cells take their cues