Induced Pluripotent Stem Cells Turned Into Extra-Ruthless Natural Killer Cells

Natural killer cells don’t have to be natural born natural killer cells. In fact, mass produced natural killer cells—that is, natural killer (NK) cells derived from induced pluripotent stem cells (iPSCs)—can be more persistent, more effective killers, reported scientists based at the University of California, San Diego (UCSD). These scientists say that one way to turn human iPSC-derived NK cells into uninhibited killing machines is to deprive them of a gene that encodes a crucial cytokine regulator. Read more…