Discovery could help reverse glucocorticoid resistance in some young leukemia patients

St. Jude Children’s Research Hospital study lays the foundation for more effective treatment of childhood leukemia and a wide range of other disorders using small molecules to reverse glucocorticoid resistance Memphis, Tennessee, May 4, 2015 Researchers led by St. Jude Children’s Research Hospital scientists have identified a mechanism that helps leukemia cells resist glucocorticoids, a

Common mutation is culprit in acute leukemia relapse

ScienceDaily, by Staff ~ March 6, 2014 Harvard stem cell scientists have identified a mutation in human cases of acute lymphoblastic leukemia that likely drives relapse. The research, published in Cancer Cell, could translate into improved patient care strategies for this particular blood cancer, which typically affects children but is more deadly in adults. In

Technique Directs Immune Cells to Target Leukemia

National Institutes of Health ~ by Harrison Wein, Ph.D. A type of targeted immunotherapy induced remission in adults with an aggressive form of leukemia that had relapsed in 5 patients. The early results of this ongoing trial highlight the potential of the approach. A lymphoblast, an abnormal cell occurring in lymphoblastic leukemia. Image by David