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Experimental arthritis drug prevents stem cell transplant complication

An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem cell transplants, new research from Washington University School of Medicine in St. Louis shows. Studying mice, the researchers found the drug prevented what’s known as graft-versus-host disease, a debilitating, sometimes lethal condition that develops when transplanted stem cells

Shriners opens new lab to WashU scientists making breakthroughs in arthritis

By Michele Munz St. Louis Post-Dispatch May 20, 2017 A multimillion-dollar lab opened this week at Shriners Hospital for Children, signaling a powerful collaboration that allows leading scientists at Washington University School of Medicine to perform cutting edge research at the philanthropic hospital. Staffed with 30 scientists from the medical school, the lab is focused on

UC Davis licenses novel compound that helps stem cells regenerate bone to treat bone diseases

March 3, 2017 Hybrid molecule LLP2A-Alendronate could have implications for osteonecrosis, fractures, osteoporosis and inflammatory arthritis. The University of California, Davis, is pleased to announce a licensing agreement with Regenerative Arthritis and Bone Medicine, Inc. (RABOME) for a class of drugs developed at UC Davis that hold potential for treating diseases associated with bone loss

McEwen Centre researchers unlock ability to create human articular cartilage

First-of-its-kind discovery allows for closer study of osteoarthritis, sets stage for repair of defective joints TORONTO, May 11, 2015 /CNW/ - A team of scientists, led by Drs. Gordon Keller and April Craft from the McEwen Centre for Regenerative Medicine in Toronto has been able to generate articular chondrocytes and cartilage tissue from human pluripotent

Surgeons create ‘new’ knee cartilage from stem cells in hip

Medical News Today, by Staff ~ July 24, 2014 Surgeons in Southampton have pioneered a new knee operation that could prevent the development of arthritis - and extend sporting careers. The procedure, which is currently being trialled at Southampton General Hospital, involves coating damaged cartilage with stem cells, taken from a patient's own hip, and

Arthritis Genetics Analysis Aids Drug Discovery

National Institutes of Health, by Carol Torgan, Ph.D. ~ January 13, 2014 An international research team identified 42 new areas in the human genome associated with rheumatoid arthritis—and found that many are already the targets of drugs approved for other conditions. The findings hint at new treatment approaches for the disease. DNA helixes in pill

January 15th, 2014|Categories: General News|Tags: , , |

Missouri startup raises near $1M to commercialize novel collagen scaffold for soft tissue therapeutic applications

Med City News, by Lindsey Alexander ~ July 25, 2013 Dermelle, LLC (aka EternoGen, LLC), a Columbia, Missouri-based startup that works with collagen scaffolds for soft tissue therapeutic applications, has raised $920,427 to close its series A funding. This money will pay for the “full spectrum of safety tests” and pilot human studies to position

Obesity, aging genes may play role in arthritis

March 19, 2013 By Jim Dryden Studying gene activity in tissue removed from injured knees, researchers at Washington University School of Medicine in St. Louis have found that genes related to obesity and aging may contribute to the development of osteoarthritis. Osteoarthritis is the most common knee disorder. The problem involves the breakdown of cartilage, causing pain, swelling