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New approach to developing antidepressants

An estimated 13 percent of Americans take antidepressant drugs for depression, anxiety, chronic pain or sleep problems. For the 14 million Americans who have clinical depression, roughly one third don’t find relief with antidepressants. But now, researchers at Washington University School of Medicine in St. Louis and Sage Therapeutics in Boston are trying a different

August 20th, 2018|Categories: Around The State, Depression|Tags: , , , |

Brain tumors occur often in kids with common genetic syndrome

The frequency of brain tumors has been underestimated in children with the common genetic syndrome neurofibromatosis type 1 (NF1), according to a new study. This disorder is characterized by birthmarks on the skin and benign nerve tumors that develop in or on the skin. Brain tumors also are known to occur in children and adults

New tools could uncover important answers for Alzheimer’s researchers

Alzheimer’s disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer’s Association. Characterized by a buildup of plaque in the brain, few animal models exist that researchers could use to study this devastating disorder. Now, a team of researchers from the University of Missouri,

Brain cancer vaccine effective in some patients

Most people with the deadly brain cancer glioblastoma die less than 18 months after diagnosis. But a multicenter clinical trial of a personalized vaccine that targets the aggressive cancer has indicated improved survival rates for such patients. The study appears May 29 in the Journal of Translational Medicine. The phase three clinical trial included 331

New Study Examines Investigational Drug Given Early to Delay or Prevent Alzheimer’s

In a new multi-center Phase II/III clinical trial, Saint Louis University researchers will test the safety and efficacy of an investigational drug’s ability to slow the decline of brain function and possibly delay or prevent Alzheimer’s disease in those at risk for Alzheimer’s disease who do not yet have symptoms of the illness. George Grossberg,

Stroke recovery improved by sensory deprivation, mouse study show

Temporarily shutting off neuronal signals to a healthy part of the brain may aid stroke recovery, according to new research in mice. The findings, from researchers at Washington University School of Medicine in St. Louis, are published Jan. 31 in Science Translational Medicine. Mice that had experienced strokes were more likely to recover the ability

February 5th, 2018|Categories: Around The State, Stroke|Tags: , , |

Memory loss from West Nile virus may be preventable

More than 10,000 people in the United States are living with memory loss and other persistent neurological problems that occur after West Nile virus infects the brain. Now, a new study in mice suggests that such ongoing neurological deficits may be due to unresolved inflammation that hinders the brain’s ability to repair damaged neurons and

January 15th, 2018|Categories: Around The State, Disease Specific|Tags: , , , |

New Clues to Alzheimer’s Disease

Researchers probing the complexities of Alzheimer’s disease have detected issues involving cellular energy production, and those problems may be an important contributor to the late-onset form of the illness. A team at Harvard-affiliated McLean Hospital tested the cells of late-onset Alzheimer’s patients and found malfunctions in their energy production, including problems with the health of

December 13th, 2017|Categories: Alzheimer's/Dementia, Disease Specific|Tags: , , |