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New tools could uncover important answers for Alzheimer’s researchers

Alzheimer’s disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer’s Association. Characterized by a buildup of plaque in the brain, few animal models exist that researchers could use to study this devastating disorder. Now, a team of researchers from the University of Missouri,

Brain cancer vaccine effective in some patients

Most people with the deadly brain cancer glioblastoma die less than 18 months after diagnosis. But a multicenter clinical trial of a personalized vaccine that targets the aggressive cancer has indicated improved survival rates for such patients. The study appears May 29 in the Journal of Translational Medicine. The phase three clinical trial included 331

New Study Examines Investigational Drug Given Early to Delay or Prevent Alzheimer’s

In a new multi-center Phase II/III clinical trial, Saint Louis University researchers will test the safety and efficacy of an investigational drug’s ability to slow the decline of brain function and possibly delay or prevent Alzheimer’s disease in those at risk for Alzheimer’s disease who do not yet have symptoms of the illness. George Grossberg,

Stroke recovery improved by sensory deprivation, mouse study show

Temporarily shutting off neuronal signals to a healthy part of the brain may aid stroke recovery, according to new research in mice. The findings, from researchers at Washington University School of Medicine in St. Louis, are published Jan. 31 in Science Translational Medicine. Mice that had experienced strokes were more likely to recover the ability

February 5th, 2018|Categories: Around The State, Stroke|Tags: , , |

Memory loss from West Nile virus may be preventable

More than 10,000 people in the United States are living with memory loss and other persistent neurological problems that occur after West Nile virus infects the brain. Now, a new study in mice suggests that such ongoing neurological deficits may be due to unresolved inflammation that hinders the brain’s ability to repair damaged neurons and

January 15th, 2018|Categories: Around The State, Disease Specific|Tags: , , , |

New Clues to Alzheimer’s Disease

Researchers probing the complexities of Alzheimer’s disease have detected issues involving cellular energy production, and those problems may be an important contributor to the late-onset form of the illness. A team at Harvard-affiliated McLean Hospital tested the cells of late-onset Alzheimer’s patients and found malfunctions in their energy production, including problems with the health of

December 13th, 2017|Categories: Alzheimer's/Dementia, Disease Specific|Tags: , , |

Brain activity ripples linked to creation of long-term memories

While we’re asleep, the brain is working to store new information as long-term memories. Storing a memory likely involves interactions between the brain’s hippocampus and parts of the cortex. Scientists have been trying to determine the precise connections by examining electrical activity within these regions of the brain. When hundreds or thousands of nerve cells,

November 25th, 2017|Categories: Alzheimer's/Dementia, Disease Specific|Tags: , , |

In autism, too many brain connections may be at root of condition

A defective gene linked to autism influences how neurons connect and communicate with each other in the brain, according to a study from Washington University School of Medicine in St. Louis. Rodents that lack the gene form too many connections between brain neurons and have difficulty learning. The findings, published Nov. 2 in Nature Communications,

November 9th, 2017|Categories: Around The State, Autism, Disease Specific|Tags: , , , |