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Macular degeneration linked to aging immune cells

As people age, their immune systems age, too. And new research at Washington University School of Medicine in St. Louis suggests that aging immune cells increase the risk for age-related macular degeneration, a major cause of blindness in the United States. Studying mice and cells from patients, the researchers found that as immune cells called

Scientists Discover New Causes of Cellular Decline in Prematurely Aging Kids

In a recent paper published in Cell Reports, Saint Louis University researchers have uncovered new answers about why cells rapidly age in children with a rare and fatal disease. The data points to cellular replication stress and a mistaken innate immune response as culprits, and the team found success in the laboratory in blocking these processes

Similarities found in cancer initiation in kidney, liver, stomach, pancreas

Recent research at Washington University School of Medicine in St. Louis demonstrated that mature cells in the stomach sometimes revert back to behaving like rapidly dividing stem cells. Now, the researchers have found that this process may be universal; no matter the organ, when tissue responds to certain types of injury, mature cells seem to

February 22nd, 2018|Categories: Around The State, Cancer|Tags: , , , |

New Clues to Alzheimer’s Disease

Researchers probing the complexities of Alzheimer’s disease have detected issues involving cellular energy production, and those problems may be an important contributor to the late-onset form of the illness. A team at Harvard-affiliated McLean Hospital tested the cells of late-onset Alzheimer’s patients and found malfunctions in their energy production, including problems with the health of

December 13th, 2017|Categories: Alzheimer's/Dementia, Disease Specific|Tags: , , |

Stem Cell Therapy Shows Promise for Retinal Degeneration

Retinal pigment epithelial (RPE) cells derived from human embryonic stem cells can be safely transplanted into the eyes of patients with retinal degeneration, with early signs of vision gain, according to pioneers in the field. Two teams of researchers reported preliminary findings from phase 1 and phase 2 trials at the American Academy of Ophthalmology (AAO)

SLU Researchers Discover BRCA Cancer Cells’ Last Defense

In a new paper published in Nature Communications, a team led by Saint Louis University researcher Alessandro Vindigni, Ph.D. shares new information about how BRCA-deficient cancer cells operate, interact with chemotherapy drugs and what may be their last-ditch effort to survive. Researchers hope their findings may lead to improved chemotherapy drugs and shed light on why

November 29th, 2017|Categories: Around The State, Cancer, Disease Specific|Tags: , , , |