Columbia University Medical Center

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Major complication of Parkinson’s therapy explained

Thu, 09/10/2015 - 2:00pm - Columbia University In a recent study, Columbia researchers have investigated why dyskinesias occur in Parkinson's disease patients: they identified a major change in the function of striatonigral GABA synapses in the basal ganglia, a brain circuit that controls movement. Pictured here in green is the striatonigral pathway. Image: Columbia Univ. Medical

Biogen, ALS Association, and Columbia University Med Center to Explore ALS Genetics

Source: © iceteastock/Fotolia.com Aug. 18, 2015 - Biogen, the ALS Association, and Columbia UniversityMedical Center (CUMC) agreed to collaborate to better understand the differences and commonalities in the ALS disease process and how genes influence the clinical features of the disease. The project, “Genomic Translation for ALS Clinical care” (GTAC), will involve a combination of next-generation

An Innovative Algorithm is Helping Scientists Decipher How Drugs Work Inside the Body

July 23, 2015 Posted in: Research Researchers at Columbia University Medical Center (CUMC) have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body. The study, published in the journal Cell, could help researchers create drugs that are more efficient and less prone to side effects, suggest ways

New Color Blindness Cause Identified

Finding suggests potential therapeutic targets June 1, 2015 A rare eye disorder marked by color blindness, light sensitivity, and other vision problems can result from a newly discovered gene mutation identified by an international research team, including scientists from Columbia University Medical Center (CUMC). The findings, which were published today in the online edition of

Immunotherapy: New Hope for Patients with Advanced Lung Cancer

First steps toward precision medicine for a deadly disease March 12, 2015 In the late 1800s, a New York surgeon named William Coley noticed that some patients with cancer seemed to fare better if they developed an infection after undergoing surgery. Suspecting that the immune system played a role in this mysterious response, he tried

Uncovering Clues to the Genetic Cause of Schizophrenia

Bioscience Technology, Source: Columbia University Medical Center ~ May 29, 2014 The overall number and nature of mutations—rather than the presence of any single mutation—influences an individual’s risk of developing schizophrenia, as well as its severity, according to a study by Columbia University Medical Center researchers published in the latest issue of Neuron. The findings

First disease-specific human embryonic stem cell line by nuclear transfer

ScienceDaily, Source: New York Stem Cell Foundation ~ April 28, 2014 Using somatic cell nuclear transfer, a team of scientists led by Dr. Dieter Egli at the New York Stem Cell Foundation (NYSCF) Research Institute and Dr. Mark Sauer at Columbia University Medical Center has created the first disease-specific embryonic stem cell line with two

Changes Responsible For Alzheimer’s Development Discovered

redOrbit, by redOrbit Staff & Wire Reports By combining high-resolution functional MRI (fMRI) imaging scans in Alzheimer’s disease patients with mouse models of the neurodegenerative condition, researchers from Columbia University Medical Center (CUMC) have gained new insights into how, where and why the disease starts and spreads. The study, which was published Sunday in the

Stem Cell Breakthrough Could Eliminate Lung Transplants

NOKOMIS, Fla.--(BUSINESS WIRE)--December 03, 2013-- As fast-growing biotech company Rainbow Coral Corp. (OTCBB: RBCC) works to deliver new cutting-edge treatments in the field of regenerative medicine, a major new breakthrough could soon lead to growing new lungs for patients in a laboratory. Researchers at Columbia University Medical Center (CUMC) recently reported success in transforming human

Stem Cells Restore Sight in Mouse Model of Retinitis Pigmentosa

Thursday, February 25, 2010 By: Science Daily An international research team led by Columbia University Medical Center successfully used mouse embryonic stem cells to replace diseased retinal cells and restore sight in a mouse model of retinitis pigmentosa. This strategy could potentially become a new treatment for retinitis pigmentosa, a leading cause of blindness that