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FDA Approves First-of-a-Kind Test for Cancer Gene Profiling

U.S. regulators have approved a first-of-a-kind test that looks for mutations in hundreds of cancer genes at once, giving a more complete picture of what’s driving a patient’s tumor and aiding efforts to match treatments to those flaws. The U.S. Food and Drug Administration approved Foundation Medicine’s test for patients with advanced or widely spread cancers, and

December 12th, 2017|Categories: Cancer, Disease Specific|Tags: , , |

In autism, too many brain connections may be at root of condition

A defective gene linked to autism influences how neurons connect and communicate with each other in the brain, according to a study from Washington University School of Medicine in St. Louis. Rodents that lack the gene form too many connections between brain neurons and have difficulty learning. The findings, published Nov. 2 in Nature Communications,

November 9th, 2017|Categories: Around The State, Autism, Disease Specific|Tags: , , , |

Gene changes may increase risk of Tourette syndrome

Tourette syndrome is a neurological disorder that is usually diagnosed in childhood. It causes repetitive, involuntary movements or noises called tics. Many with Tourette syndrome experience other problems including inattention, hyperactivity, and impulsivity, as well as obsessive-compulsive symptoms such as intrusive thoughts and worries. Symptoms are usually worst during the early teen years, with improvements

Changing cell behavior could boost biofuels, medicine

By Beth Miller November 7, 2016 An engineer at Washington University in St. Louis developed an algorithm that suggests gene to remove from certain cells, such as yeast, to get them to perform a normal activity in a different environment or situation. A computer scientist at Washington University in St. Louis has developed a way

New findings shed light on fundamental process of DNA repair

September 8, 2015 Inside the trillions of cells that make up the human body, things are rarely silent. Molecules are constantly being made, moved, and modified — and during these processes, mistakes are sometimes made. Strands of DNA, for instance, can break for any number of reasons, such as exposure to UV radiation, or mechanical

Finding Factors that Affect Huntington’s Disease Onset

August 31, 2015 At a Glance Researchers used a novel strategy to find genetic factors associated with the onset of Huntington’s disease symptoms. The approach may lead to ways to predict the onset and progression of disease as well as suggest new therapeutic approaches. Huntington’s disease is an inherited neurodegenerative disorder. Symptoms usually begin in

The CRISPR Revolution at MU

By Caleb O’Brien | MU Bond Life Sciences Center August 19, 2015 James Amos-Landgraf needed a pig. The assistant professor of comparative medicine and genetics at the University of Missouri had joined forces with a startup company developing a tool to detect early colon cancer-causing lesions. They already tried out a rat-sized model, but still

Biologist investigates how gene-swapping bacteria evade antibiotics

Mon, 08/17/2015 - 1:45pm Univ. of Texas at Dallas Dr. Kelli Palmer (center), assistant professor of biological sciences at The Univ. of Texas at Dallas, and doctoral student Wenwen Huo investigate the underlying mechanisms by which bacteria acquire antibiotic resistance genes from one another. Photo: UT DallasA scientific peek into bacteria boudoirs is revealing how