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Navigating the Genome to Cure Deafness

A new Tel Aviv University study solves a critical piece of the puzzle of human deafness by identifying the first group of long non-coding RNAs (lncRNAs) in the auditory system. "The research on long non-coding RNAs is crucial to understanding how gene expression and regulatory elements influence the auditory system," says Prof. Karen Avraham, Vice

November 11th, 2017|Categories: Disease Specific, Hearing|Tags: , |

$10 million gift supports genome engineering center

Washington University School of Medicine in St. Louis has received a $10 million commitment from longtime benefactors George and Debra Couch to support research that advances personalized medicine. In recognition of their generosity, the recently built research building at 4515 McKinley Ave. has been named the Debra and George W. Couch III Biomedical Research Building.

November 6th, 2017|Categories: Around The State|Tags: , , |

NIH accelerates the use of genomics in clinical care

New funding awards focus on diverse and underserved populations. The National Institutes of Health (NIH) is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care. The new awards will generate innovative approaches and best practices to ensure that the effectiveness of genomic medicine can be applied to

August 14th, 2017|Categories: General News|Tags: , |

Genome sequenced of enterovirus D68 circulating in St. Louis

Washington University in St. Louis, by Julia Evangelou Straight ~ October 28, 2014 Researchers at Washington University School of Medicine in St. Louis have sequenced the genome of enterovirus D68 sampled from patients treated at St. Louis Children’s Hospital. Nationwide, the virus has spread rapidly in recent months and caused severe respiratory illness in young

Genome regions once mislabeled ‘junk’ linked to heart failure

Washington University in St. Louis, by Julia Evangelou Strait ~ April 24, 2014 Large sections of the genome that were once referred to as “junk” DNA have been linked to human heart failure, according to research from Washington University School of Medicine in St. Louis. So-called junk DNA was long thought to have no important

Genome regions once mislabeled ‘junk’ linked to heart failure

April 24, 2014 By Julia Evangelou Strait, Senior Medical Science Writer, Washington University in St. Louis [ROBERT BOSTON photo] Jeanne Nerbonne, PhD, led a team that found a link between human heart failure and sections of the genome once referred to as junk DNA. Large sections of the genome that were once referred to as “junk”

Elephant shark genome decoded ~ New insights gained into bone formation and immunity

Washington University in St. Louis, by Caroline Arbanas ~ January 8, 2014 An international team of researchers has sequenced the genome of the elephant shark, a curious-looking fish with a snout that resembles the end of an elephant’s trunk. The elephant shark and its cousins the sharks, rays, skates and chimaeras are the world’s oldest-living

Different Cancers Can Share Genetic Signatures

National Institutes of Health, by Dr. Francis Collins ~ October 22, 2013 Cancer is a disease of the genome. It arises when genes involved in promoting or suppressing cell growth sustain mutations that disturb the normal stop and go signals. There are more than 100 different types of cancer, most of which derive their names

Cancer’s Origins Revealed

RegenerativeMedicine.net, by Staff ~ September 9, 2013 Researchers have provided the first comprehensive compendium of mutational processes that drive tumor development. Together, these mutational processes explain most mutations found in 30 of the most common cancer types. This new understanding of cancer development could help to treat and prevent a wide-range of cancers. Each mutational

September 9th, 2013|Categories: Cancer, Disease Specific|Tags: , , |

Largest cancer gene database made public

Reuters, by Deena Beasley ~ July 15, 2013 National Cancer Institute scientists have released the largest-ever database of cancer-related genetic variations, providing researchers the most comprehensive way so far to figure out how to target treatments for the disease. Open access worldwide to the new database, based on genome studies, is expected to help researchers