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A 3-D model of a human heart ventricle

Harvard University researchers have bioengineered a three-dimensional model of a human left heart ventricle that could be used to study diseases, test drugs and develop patient-specific treatments for heart conditions such as arrhythmia. The tissue is engineered with a nanofiber scaffold seeded with human heart cells. The scaffold acts like a 3D template, guiding the

Scientists ID source of damaging inflammation after heart attack

Scientists have zeroed in on a culprit that spurs damaging inflammation in the heart following a heart attack. The guilty party is a type of immune cell that tries to heal the injured heart but instead triggers inflammation that leads to even more damage. Further, the researchers have found that an already approved drug effectively

MU School of Medicine researcher uncovers clue to as to how disease processes develop

A new study could have major implications for our understanding of disease processes for conditions such as autoimmunity, atherosclerosis and heart failure, potentially leading to better prevention and treatment. Dr. Edward T.H. Yeh, chairman of the Department of Medicine and director of the Center for Precision Medicine at the University of Missouri School of Medicine, has been leading a team of

Tension Makes the Heart Grow Stronger

By taking videos of a tiny beating zebrafish heart as it reconstructs its covering in a petri dish, scientists have captured unexpected dynamics of cells involved in tissue regeneration. They found that the depleted heart tissue regenerates itself in a wave, led by a front of fast-moving, supersized cells and trailed by smaller cells that

$10 million DNA sequencing effort aims to shed light on lung diseases

Research is part of national project to understand genetic roots of heart, lung, blood, sleep disorders by Julia Evangelou Strait Washington University’s McDonnell Genome Institute has received $10 million from the National Heart, Lung and Blood Institute (NHLBI) to sequence the DNA of people from diverse ethnic backgrounds, in an effort to identify the genetic

Regenerating defective heart tissue in babies using amniotic stem cells

Medical News Today, by Staff ~ October 11, 2013 Researchers at the University of Michigan Department of Surgery have begun testing an alternative to embryonic stem cells that could one day regenerate muscle tissue for babies with congenital heart defects. A research-in-progress report on this new approach, which uses amniotic stem cells, was presented at