Gut microbes’ metabolite dampens proliferation of intestinal stem cells

Finding may provide clues to limitations of potential IBD treatment By  Tamara Bhandari June 2, 2016 Intestinal stem cells are sequestered in pockets in the lining of the intestine to avoid contact with a metabolite produced by beneficial microbes in the gut. That metabolite — butyrate — restricts the proliferation of stem cells, shown here in