iPS cells

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Engineering human stem cells to model the kidney’s filtration barrier on a chip

May 10, 2017 A glomerulus-on-a-chip lined by human stem cell-derived kidney cells could help model patient-specific kidney diseases and guide therapeutic discovery By Benjamin Boettner (BOSTON) — The kidney – made up of about a million tiny units that work to filter blood, constantly rids the body of undesired waste products to form urine while

The Stem-Cell Revolution Is Coming — Slowly

By WALLACE RAVVEN JAN. 16, 2017 The New York Times In 2001, President George W. Bush issued an executive order banning federal funding for new sources of stem cells developed from preimplantation human embryos. The action stalled research and discouraged scientists. Five years later, a Kyoto University scientist, Shinya Yamanaka, and his graduate student, Kazutoshi

Scientists generate pluripotent stem cells with more stable genomes

August 28, 2015 at 1:48 AM Damaged tissue, such as pancreas, heart, and neuronal tissue, which is regenerated to treat cardiovascular diseases, diabetes, or neurodegenerative diseases. This is one of the ambitious scenarios to which regenerative medicine aspires and that is being announced as one of the great promises of twenty-first century biomedicine for the

August 28th, 2015|Categories: Uncategorized|Tags: , , |

Scientists grow ‘mini-lungs’ to aid the study of cystic fibrosis

Scientists at the University of Cambridge have successfully created ‘mini-lungs’ using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease. We can use these 'mini-lungs' to learn more about key aspects of serious diseases –

Clinical trial using iPS cells litmus test for promoting regenerative medicine

The Japan Times, by The Yomiuri Shimbun ~ September 16, 2014 The latest clinical trial is the first step of epoch-making research that could evolve into regenerative medicine. After careful safety assessment, putting the latest result into practical use should be promoted. A team led by RIKEN ophthalmologist Masayo Takahashi transplanted retina cells produced from

Light-sensitive retina created with human stem cells

Medical News Today, by Marie Ellis ~ June 10, 2014 Researchers from the Johns Hopkins University School of Medicine in Baltimore, MD, have created a miniature human retina in a dish from human stem cells, which they say can sense light. They are hopeful their creation could eventually lead to technologies one day that restore

Aging accelerated in stem cells to study age-related diseases like Parkinson’s

Medical News Today, by Staff ~ December 10, 2013 Stem cells hold promise for understanding and treating neurodegenerative diseases, but so far they have failed to accurately model disorders that occur late in life. A study published by Cell Press in the journal Cell Stem Cell has revealed a new method for converting induced pluripotent

Human clinical studies of iPS cells to treat Parkinson’s Disease coming very soon

Knoepfler Lab Stem Cell Blog, by Paul Knoepfler ~ June 8, 2013 A Japanese team of researchers led by Dr. Jun Takahashi, professor at Kyoto University is reportedly aiming to start in human studies of an induced pluripotent stem (iPS) cell-based treatment for Parkinson’s Disease (PD) as early as fiscal year (FY) 2014. In Japan

Researchers Demonstrate Use of Stem Cells to Analyze Causes, Treatment of Diabetes

June 17, 2013 — Science Daily - A team from the New York Stem Cell Foundation (NYSCF) Research Institute and the Naomi Berrie Diabetes Center of Columbia University has generated patient-specific beta cells, or insulin-producing cells, that accurately reflect the features of maturity-onset diabetes of the young (MODY). The researchers used skin cells of MODY patients