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First steps in basic biological process that could be harnessed to make therapeutic cells

April 16, 2015Pioneer factor binding chromosomes is shown. Credit: Kenneth S. Zaret, Ph.D., Perelman School of Medicine, University of PennsylvaniaUnderstanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves. By knowing the principles that underlie the intricate steps

University of Iowa Research Team Finds New Genetic Cause of Blinding Eye Disease

Tuesday, August 9, 2011 By: University of Iowa Health Care A combination of exom sequencing and analysis of retina tissue generated from induced pluripotent stem cells identified a mutation in a gene not previously associated with human eye disease as the likely cause of a retinitis pigmentosa. Combining the expertise of several different labs, University

Bypassing Stem Cells, Scientists Make Neurons Directly from Human Skin

Thursday, August 4, 2011 By: Cell Press Researchers have come up with a recipe for making functional neurons directly from human skin cells, including those taken from patients with Alzheimer's disease. The new method may offer a critical short cut for generating neurons for replacement therapies of the future, according to research published in the

Biology’s New Supermodel

Wednesday, July 20, 2011 By: Megan Scudellari, The Scientist Induced pluripotent stem cells are biology's hottest new tool for understanding human disease. Move over mice. Human induced pluripotent stem (iPS) cells are making strides to become the next best thing in translational research—disease-specific human cells grown in a dish. Using a variety of approaches, researchers

July 20th, 2011|Categories: ALS, Disease Specific|Tags: , , , |

Researchers Report Progress Using iPS Cells to Reverse Blindness

Wednesday, June 15, 2011 By: Indiana University-Purdue University Indianapolis Researchers have used cutting-edge stem cell technology to correct a genetic defect present in a rare blinding disorder, another step on a promising path that may one day lead to therapies to reverse blindness caused by common retinal diseases such as macular degeneration and retinitis pigmentosa