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New Cellular Approach Found to Control Progression of Chronic Kidney Disease

Researchers have demonstrated for the first time that extracellular vesicles - tiny protein-filled structures - isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage in mice with a type of chronic kidney disease. The findings, by a research team at the Saban Research Institute of Children's

Kidney disease increases risk of diabetes, study shows

Diabetes is known to increase a person’s risk of kidney disease. Now, a new study from Washington University School of Medicine in St. Louis suggests that the converse also is true: Kidney dysfunction increases the risk of diabetes. Further, the researchers deduced that a likely culprit of the two-way relationship between kidney disease and diabetes

Scientists find culprit responsible for calcified blood vessels in kidney disease

Stem cell finding informs research to prevent hardening of arteries By Julia Evangelou Strait September 8, 2016 A new study indicates that stem cells called Gli1 cells (shown in red) are responsible for depositing calcium in the arteries, increasing the risk of atherosclerosis. Over time, the condition can lead to cardiovascular disease and is especially

Washington University develops genetic test for inherited kidney diseases

March 26, 2015 By Michael C. Purdy and Gaia Remerowski GPS A new test from Washington University’s Genomic Pathology Services will help physicians quickly zero in on genetic mutations that may be contributing to kidney disease. Many kidney disorders are difficult to diagnose. To address this problem, scientists and clinicians have developed a diagnostic test

Doctors getting clearer picture of how to slow or stop kidney disease in children

BY ALAN BAVLEY THE KANSAS CITY STAR 03/19/2015   Marley Martinac, 2, is a kidney patient at Children’s Mercy Hospital, but mom Katie Martinac says the girl is as spunky as ever. Marley used her Doc McStuffins mobile cart to give her dog, Kamo, a checkup at the family’s home in Bates City. KEITH MYERS THE KANSAS

Researchers investigate use of pig kidneys for human transplant

According to the National Kidney Foundation, around 96,645 patients in the US are awaiting kidney transplants as a result of kidney failure. However, less than 17,000 kidney transplantations are carried out each year due to a shortage of donors. But a new option could soon be available - in the form of pig kidneys. Researchers

‘Mini-Kidney’ Structures Generated from Human Stem Cells for First Time

ScienceDaily, by Staff ~ November 17, 2013 Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology. Now, a team of researchers led by scientists at the Salk Institute for

Surgeons implant bioengineered vein

Thu, 06/06/2013 - 2:19pm - R & D Magazine Using technology developed at Duke and at a spin-off company it started called Humacyte, the bioengineered vein is made by cultivating donated human cells on a tubular scaffold to form a vessel. In a first-of-its-kind operation in the United States, a team of doctors at Duke

Lab-Grown Kidneys Function in Rats

April 29, 2013 - by Vicki Contie, Assistant Editor, NIH Research Matters,  Scientists have created artificial kidneys that can filter blood and produce urine when transplanted into rats. With further development, this approach could help the many patients who await organ transplants because their own kidneys no longer work. A decellularized rat kidney in a

Rat Kidneys Made in Lab Point to Aid for Humans

The New York Times ~ By Henry Fountain Researchers at Massachusetts General Hospital in Boston have made functioning rat kidneys in the laboratory, a bioengineering achievement that may one day lead to the ability to create replacement organs for people with kidney disease. The scientists said the rat kidneys produced urine in the laboratory as