leukemia

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FDA Approves Novel Leukemia Treatment that Could Be First U.S. Gene Therapy

By Linda Johnson, Associated Press A treatment for a common childhood blood cancer could become the first gene therapy available in the U.S. A Food and Drug Administration advisory panel voted 10-0 on Wednesday in favor of the leukemia treatment developed by the University of Pennsylvania and Novartis Corp. The FDA usually follows recommendations from

July 19th, 2017|Categories: Cancer, Uncategorized|Tags: , , |

F.D.A. Panel Recommends Approval for Gene-Altering Leukemia Treatment

The New York Times By DENISE GRADY A Food and Drug Administration panel opened a new era in medicine on Wednesday, unanimously recommending that the agency approve the first-ever treatment that genetically alters a patient’s own cells to fight cancer, transforming them into what scientists call “a living drug” that powerfully bolsters the immune system

July 14th, 2017|Categories: Cancer, Disease Specific|Tags: , , , , |

New immunotherapy for leukemia shows promise in small clinical trial

'Training' immune cells boosts effectiveness in patients with AML By Julie Evangelou Strait September 21, 2016 A new type of immunotherapy shows promise against cases of acute myeloid leukemia (AML) that recur after treatment or that never respond to therapy in the first place. A small clinical trial at Washington University School of Medicine in St. Louis

New cancer treatment is showing “extraordinary” results

CBS NEWS February 17, 2016, 11:05 AM A cancer therapy involving a patient's own immune cells is showing extraordinary results in leukemia patients, researchers say. In the latest study, U.S. researchers used genetically modified T-cells in 35 terminally ill patients with leukemia, and 94 percent went into remission. "A type of blood cell in the

Researchers find new clue to halting leukemia relapse

Rice, Baylor, MD Anderson team creates molecule that attacks chemo-inhibiting protein  HOUSTON – (Sept. 8, 2015) – A protein domain once considered of little importance may be key to helping patients who are fighting acute myeloid leukemia (AML) avoid a relapse. Researchers at Rice University, working with colleagues at Baylor College of Medicine and the

September 8th, 2015|Categories: Cancer|Tags: , , , , , |

Relapse, poor survival in acute leukemia linked to genetic mutations that persist in remission ​​​

August 25, 2015 By Caroline Arbanas For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations – detected after initial treatment with chemotherapy – are associated with an increased risk of relapse and poor survival. Using genetic profiling to study bone marrow samples from patients with acute myeloid leukemia (AML), researchers

UTSW Researchers Find Molecule Able to Accelerate Tissue Regeneration Upon Injury

July 20, 2015 Patricia Silva - A study recently published in the renowned journal Science revealed a molecule able to accelerate tissue regeneration after bone marrow transplantation and other tissue injuries in mice. The study is entitled “Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration” and was led by researchers at the University of

Medical researcher from Oakville making strides in fighting leukemia

July 3, 2015, By Abigail Cukier Dr. Paul Spagnuolo's work published in Cancer Research Photo courtesy Light Imaging/University of Waterloo Dr. Paul Spagnuolo Avocados are having a moment. Touted for their nutritional benefits and rich, creamy taste, they are popping up in trendy restaurants and fast food chains everywhere. But a local medical researcher has

New technology may reduce deadly complication of bone marrow transplants

May 11, 2015 By Julia Evangelou Strait, Washington University RIDDELL AND APPELBAUM, 2007 Bone marrow transplants are a common treatment for leukemia. A potentially dangerous side effect called graft-versus-host disease occurs when donor T cells from the transplant attack the body’s tissues, such as the skin (above), in addition to the cancer cells. Researchers have developed

Discovery could help reverse glucocorticoid resistance in some young leukemia patients

St. Jude Children’s Research Hospital study lays the foundation for more effective treatment of childhood leukemia and a wide range of other disorders using small molecules to reverse glucocorticoid resistance Memphis, Tennessee, May 4, 2015 Researchers led by St. Jude Children’s Research Hospital scientists have identified a mechanism that helps leukemia cells resist glucocorticoids, a