National Institutes of Health

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Six New Genetic Risk Factors for Parkinson’s Found

Bioscience Technology, Source: NIH ~ July 28, 2014 Using data from over 18,000 patients, scientists have identified more than two dozen genetic risk factors involved in Parkinson’s disease, including six that had not been previously reported. The study, published in Nature Genetics, was partially funded by the National Institutes of Health (NIH) and led by

Isolated Cancer Cells May Lead to Personalized Treatments

National Institutes of Health, by Shu Hui Chen, Ph.D. ~ July 28, 2014 Cells shed from tumors enter the bloodstream in very low numbers and circulate through the body. These circulating tumor cells (CTCs) can take root elsewhere, causing the spread of the cancer to other organs, a process called metastasis. As cancers grow and

Researchers Flex New Muscle in SMA Drug Development

July 16, 2014 By Paige Blankenbuehler Lauren and Claire Gibbs share contagious laughter, ambition and a charismatic sarcasm. Both are honor students at Shawnee Mission East High School in a Kansas City suburb. They also share a neuromuscular disease called spinal muscular atrophy (SMA), designated as an “orphan disease” because it affects fewer than 200,000

Stem Cell Transplant Reverses Sickle Cell Disease in Adults

National Institutes of Health, by Staff ~ July 14, 2014 Sickle cell disease is an inherited blood disorder that affects more than 90,000 Americans, mostly of African descent. The condition arises from a genetic defect that alters the structure of hemoglobin, the oxygen-carrying protein found in red blood cells. The modified hemoglobin causes normally round

Marrow Transplants Can Reverse Adult Sickle Cell

Bioscience Technology, by Lindsey Tanner ~ July 1, 2014 Bone marrow transplants can reverse severe sickle cell disease in adults, a small study by government scientists found, echoing results seen with a similar technique used in children. The researchers and others say the findings show age need not be a barrier and that the technique

MU Researcher Receives $1.5 Million Grant from the National Institutes of Health to Study Vascular Factors in Alzheimer’s Disease

University of Missouri, by Jeff Sossamon ~ May 19, 2014 Alzheimer’s is a progressive brain disease that affects older adults, slowly destroys their memories and may cause dementia. According to estimates from the National Institutes of Health (NIH), the disease may affect as many as 5.1 million Americans. Now, with the help of a $1.5

NIH Will No Longer Require Special Review for U.S. Gene Therapy Trials

Science Insider, by Jocelyn Kaiser ~ May 22, 2014 In a milestone for the field of gene therapy, the National Institutes of Health (NIH) will no longer subject all proposed gene therapy clinical trials to review by a special federal advisory committee. “Given the progress in the field, I am confident that the existing regulatory

Paralyzed Men Regain Movement With Spinal Stimulation

National Institutes of Health, by Staff ~ April 14, 2014 Four young men paralyzed below the chest because of spinal cord injuries were able to regain control of some movement after receiving an experimental spinal stimulation therapy. If confirmed in larger studies, this type of treatment may one day improve outcomes for people living with

NIH, industry and non-profits join forces to speed validation of disease targets

Goal is to develop new treatments earlier, beginning with Alzheimer’s, type 2 diabetes, and autoimmune disorders The National Institutes of Health, 10 biopharmaceutical companies and several nonprofit organizations today launched an unprecedented partnership to transform the current model for identifying and validating the most promising biological targets of disease for new diagnostics and drug development.

NIH Unleashing Alzheimer’s Project Whole Genome Sequence Data

GenomeWeb, by GenomeWeb Staff Reporter ~ December 2, 2013 NEW YORK (GenomeWeb News) –The National Institutes of Health has begun dumping volumes of genomic data from its large-scale Alzheimer's disease study into the public realm for the research community to begin searching for clues about ways to better understand, treat, and diagnose the disease, NIH