Rogue breast tumor proteins point to potential drug therapies

Such treatment options are missed by genomic sequencing By Julia Ezangelou Strait March 28, 2017 For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies. But this approach overlooks another potential marker — rogue proteins — that may

Beta cells from love handles

April 11, 2016 Researchers at ETH Zurich have managed to use a synthetic genetic program to instruct stem cells taken from fatty tissue to become cells that are almost identical to natural beta cells. This brings them a major step closer to a personal repair kit for diabetes sufferers. Researchers led by Martin Fussenegger, Professor

The switch that might tame the most aggressive of breast cancers

Tuesday 31 March 2015 at 1am PST Australian researchers have found that so-called 'triple-negative breast cancers'1 are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad. Id4+ stem cells are in red, luminal cells

A new weapon against stroke

UC Davis stem cell study uncovers the brain-protective powers of astrocytes (SACRAMENTO, Calif.) -- One of regenerative medicine's greatest goals is to develop new treatments for stroke. So far, stem cell research for the disease has focused on developing therapeutic neurons — the primary movers of electrical impulses in the brain — to repair tissue