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NIH accelerates the use of genomics in clinical care

New funding awards focus on diverse and underserved populations. The National Institutes of Health (NIH) is awarding $18.9 million towards research that aims to accelerate the use of genome sequencing in clinical care. The new awards will generate innovative approaches and best practices to ensure that the effectiveness of genomic medicine can be applied to

August 14th, 2017|Categories: General News|Tags: , |

Trump Keeps Francis Collins, MD, as NIH Chief

Francis Collins, MD, PhD, the director of the National Institutes of Health (NIH) and an appointee of Barack Obama, will keep his job in the Trump administration, the White House announced yesterday. One of Dr Collins' challenges going forward will be protecting the NIH from a massive budget cut proposed by President Donald Trump. The

June 13th, 2017|Categories: General News|Tags: , , |

Treatment shows promise in models of fatal neurological disorders

April 25, 2017 At a Glance Researchers found that a gene-silencing drug can reverse or improve symptoms in mouse models of ataxia and amyotrophic lateral sclerosis. The results suggest a new possible therapy for these two untreatable neurological diseases. A drug designed to silence a gene called ataxin 2 improved neuron function in mouse models

$7 million aimed at illuminating the genetics of Alzheimer’s disease

Researchers working to identify genetic factors that raise, lower disease risk by Tamara Bhandari•March 13, 2017 OSCAR HARARI Studies are underway to identify the genetic networks that affect a person's risk of developing Alzheimer's disease. The researchers are aiming to find ways to predict who will develop the neurodegenerative disease, at what age and how

Stem cell transplants may induce long-term remission of multiple sclerosis

Wednesday, February 1, 2017 Encouraging results help set stage for larger studies. New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system. “...these

Sickle Cell Disease: Gene-Editing Tools Point to Possible Ultimate Cure

Posted on October 25, 2016 by Dr. Francis Collins Caption: An electron micrograph showing two red blood cells, one normal (right) and the other (left) deformed by crystalline hemoglobin into the “sickle” shape characteristic of patients with sickle cell disease. Credit: Frans Kuypers: RBClab.com, UCSF Benioff Children’s Hospital Oakland Scientists first described the sickle-shaped red

Stem cell therapy heals injured mouse brain

Monday, August 22, 2016 Animal study examines method for restoring brain cells killed by stroke or other neurological diseases. Scientists and clinicians have long dreamed of helping the injured brain repair itself by creating new neurons, and an innovative NIH-funded study published today in Nature Medicine may bring this goal much closer to reality. A

August 22nd, 2016|Categories: Stroke|Tags: , , , |

Stem cells grown on scaffold mimic hip joint cartilage

August 9, 2016 NIH Research Matters At a Glance Adult fat-derived stem cells grown on a 3-D scaffold that mimicked a hip joint surface formed cartilage and maintained the correct shape. The cells were induced to make high levels of an anti-inflammatory protein on demand that prevents joint degradation. The findings could lead to new

Study Details Process Involved in Parkinson’s Disease

Aug. 24, 2015 NIH Research Matters At a Glance Researchers detailed how cells dispose of damaged mitochondria, a process that can lead to neurodegenerative and other diseases when gone awry. The results suggest a new pathway to target to treat disorders linked to faulty mitochondrial disposal, including some forms of Parkinson’s disease and ALS. Roughly

August 24th, 2015|Categories: Parkinson's Disease|Tags: , , , |