Parkinson’s disease

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Scientists find a role for Parkinson’s gene in the brain

A new study published in the journal Neuron sheds light on the normal function of LRRK2, the most common genetic cause for late-onset Parkinson’s disease. The study was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. For more than 10 years, scientists have known that

$3.7 million to help research neurological disorders linked to manganese

Manganese – found in smoke from steel production and coal fires – has been linked to a range of neurological problems often seen with Parkinson’s disease: slowness, stiffness, tremors, anxiety, depression, cognitive changes, and difficulty walking and speaking. Decades ago, federal environmental and public health agencies established manganese-concentration levels of concern for human health, but

Antioxidants Early in Parkinson’s Disease May Halt Degeneration

Northwestern Medicine scientists have identified a toxic cascade that leads to neuronal degeneration in patients with Parkinson's disease (PD) and figured out how to interrupt it, reports a study published September 7 in the journal Science. Intervening with an antioxidant early in the disease process may break the degenerative cycle and improve neuron function in PD,

Medical history can point to earlier Parkinson’s disease diagnosis

Before symptoms become pronounced, there is no reliable way to identify who is on track to develop Parkinson’s disease, a debilitating movement disorder characterized by tremors, slowness of movement, stiffness, and difficulty with balance and coordination. But researchers at Washington University School of Medicine in St. Louis have analyzed Medicare claims data of more than

Your brain cells could be reprogrammed to fight Parkinson’s Disease

IN BRIEF Researchers have reprogrammed existing brain cells in mice into dopamine neurons to reduce their symptoms of Parkinson's disease. This novel approach could be used to treat Parkinson's disease with stem cells which are not transplanted, but induced from patients' own brain cells. SUPPORT CELLS TURNED SUPER CELLS Parkinson’s disease is one of the

Scientists develop a new approach for Parkinson’s disease therapy

Wednesday, August 3, 2016 - 00:19   SPECIAL TO HNN PROVIDED BY MARSHALL UNIVERSITY Last year, Dr. Elmer Price, a professor of biological sciences at Marshall University, was awarded a three-year, $350,000 research grant from the National Science Foundation. The grant funds his research into understanding neurogenesis, the process adult brains use to generate new

Major complication of Parkinson’s therapy explained

Thu, 09/10/2015 - 2:00pm - Columbia University In a recent study, Columbia researchers have investigated why dyskinesias occur in Parkinson's disease patients: they identified a major change in the function of striatonigral GABA synapses in the basal ganglia, a brain circuit that controls movement. Pictured here in green is the striatonigral pathway. Image: Columbia Univ. Medical

Inosine Trial Secures Phase III Funding to Study Effect on Slowing Parkinson’s

Posted by  Maggie McGuire Kuhl, September 01, 2015 The Michael J. Fox Foundation’s largest grant to a single investigator thus far awarded $5.6M in 2008 to Michael Schwarzschild, PhD, of Massachusetts General Hospital for a Phase II trial of inosine, a precursor to the antioxidant of urate. Observational studies had shown people with higher levels of

Study Details Process Involved in Parkinson’s Disease

Aug. 24, 2015 NIH Research Matters At a Glance Researchers detailed how cells dispose of damaged mitochondria, a process that can lead to neurodegenerative and other diseases when gone awry. The results suggest a new pathway to target to treat disorders linked to faulty mitochondrial disposal, including some forms of Parkinson’s disease and ALS. Roughly

August 24th, 2015|Categories: Parkinson's Disease|Tags: , , , |