Parkinson’s

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SLU Researchers Discover Structure of Protein Associated with Inflammation, Parkinson’s

In a recent paper published in Nature Communications, Saint Louis University scientists report that they have determined the structure of a key protein that is involved in the body’s inflammatory response. This finding opens the door to developing new treatments for a wide range of illnesses, from heart disease, diabetes and cancer to neurodegenerative disorders, including

‘Reprogrammed’ stem cells fight Parkinson’s disease in monkeys

LONDON (Reuters) - Scientists have successfully used “reprogrammed” stem cells to restore functioning brain cells in monkeys, raising hopes the technique could be used in future to help patients with Parkinson’s disease. Since Parkinson’s is caused by a lack of dopamine made by brain cells, researchers have long hoped to use stem cells to restore

Immune system may mount an attack in Parkinson’s disease

A new study suggests that T cells, which help the body’s immune system recognize friend from foe, may play an important role in Parkinson’s disease (PD). The study, published in the journal Nature, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. “This collaboration between

Immune response linked to Parkinson’s disease

Parkinson’s disease is a degenerative brain disorder that develops when nerve cells in the brain become impaired and eventually die. As these brain cells die, people with Parkinson’s disease may start experiencing involuntary shaking, muscle stiffness, slowed movements, problems with balance, and other symptoms. At first, only a tremor in one hand may be noticeable.

Scientists discover two repurposed drugs that arrest neurodegeneration in mice

University of Cambridge April 20, 2017 A team of scientists who a few years ago identified a major pathway that leads to brain cell death in mice, have now found two drugs that block the pathway and prevent neurodegeneration. The drugs caused minimal side effects in the mice and one is already licensed for use

Steroid originally discovered in the dogfish shark attacks Parkinson’s-related toxin in animal model

Credit: Doug Costa, NOAA/SBNMS MEDIA CONTACT: Karen Teber WASHINGTON (January 16, 2017) — A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson’s disease. The clustering of this protein, alpha-synuclein (α-synuclein), is the

Breakthrough in the production of dopamine neurons for Parkinson’s disease

Published: 29/10/2016 - Lund University, Sweden The first transplantation of stem cells in patients with Parkinson's disease is almost within reach. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients. - In our preclinical assessments of stem

Michael J. Fox Foundation supports two stem cell research projects for Parkinson’s

Harvard Teaching Hospitals funded to develop dopamine neuron replacement treatment -- Parkinson's Progression Markers Initiative making iPSCs available to broad research community -- Dopamine neurons engineered from iPSCs may hold utility as therapeutics and research tools May 25, 2016, 10:00 ET from The Michael J. Fox Foundation NEW YORK, May 25, 2016 /PRNewswire-USNewswire/ -- The