reprogramming

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Turning skin cells into blood vessel cells while keeping them young

April 6, 2017 - by Sharon Parmet Researchers from the University of Illinois at Chicago have identified a molecular switch that converts skin cells into cells that make up blood vessels, which could ultimately be used to repair damaged vessels in patients with heart disease or to engineer new vasculature in the lab. The technique, which

Beta cells from love handles

April 11, 2016 Researchers at ETH Zurich have managed to use a synthetic genetic program to instruct stem cells taken from fatty tissue to become cells that are almost identical to natural beta cells. This brings them a major step closer to a personal repair kit for diabetes sufferers. Researchers led by Martin Fussenegger, Professor

Mount Sinai Researchers Report Insights into Blood Stem Cells from Engineered Stem Cells

Building upon previous work, researchers at the Icahn School of Medicine at Mount Sinai have identified a precursor cell in the placenta and embryo of mice that can be matured in the lab to make hematopoietic stem/progenitor cells NEW YORK, NY (PRWEB) MARCH 08, 2016 Building upon previous work, researchers at the Icahn School of

Scientists Create Insulin-Producing Pancreatic Cells from Human Skin Cells

The new cells prevented the onset of diabetes in an animal model of the disease Jan. 6, 2016 SAN FRANCISCO, CA—January 6, 2016—Scientists from the Diabetes Center at UCSF and the Gladstone Institutes have successfully converted human skin cells into fully functional pancreatic cells. The new cells produced insulin in response to changes in glucose

As CIRM opens world’s largest stem cell bank, scientists ready their research

Sep 1, 2015 A $32 million public-private bank — where California researchers collect stem cells and scientists from around the world can make withdrawals — officially opened Tuesday with the aim of accelerating the use of engineered stem cells to tackle a wide range of diseases. The bank, funded by the California Institute for Regenerative

Chemical Cocktails Produce Neurons

Two research groups have devised small-molecule recipes to directly transform fibroblasts into neurons. By Kerry Grens | August 6, 2015 COURTESY OF HONGKUI DENG Over the past several years, scientists have been in hot pursuit of finding an efficient way to directly transform skin cells to brain cells—skipping an intermediate pluripotent step. Genetic approaches have

Reprogramming of DNA observed in human germ cells for first time

Monday, June 8, 2015 - University of Cambridge A team of researchers led by the University of Cambridge has described for the first time in humans how the epigenome – the suite of molecules attached to our DNA that switch our genes on and off – is comprehensively erased in early primordial germ cells prior

Johns Hopkins researchers engineer custom blood cells

Step toward new treatment for patients with sickle cell disease March 9, 2015 JOHNS HOPKINS MEDICINE Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, they report. The study represents an important step toward