Home/Tag: T-cells

CRISPR enhances cancer immunotherapy

Last year, the Food and Drug Administration approved the first cellular immunotherapies to treat cancer. These therapies involve collecting a patient’s own immune cells — called T cells — and supercharging them to home in on and attack specific blood cancers, such as hard-to-treat acute lymphoblastic leukemia and non-Hodgkin lymphoma. But so far, these T

Novel ‘Barcode’ tracking T-cells in Immunotherapy Patients identifies likely cancer

Wed, 03/01/2017 - 10:17am by Fred Hutchinson Cancer Research Center A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best suited to fight cancer. The findings will be published February

New cancer treatment is showing “extraordinary” results

CBS NEWS February 17, 2016, 11:05 AM A cancer therapy involving a patient's own immune cells is showing extraordinary results in leukemia patients, researchers say. In the latest study, U.S. researchers used genetically modified T-cells in 35 terminally ill patients with leukemia, and 94 percent went into remission. "A type of blood cell in the

New insight into how the immune system sounds the alarm

Salk scientists unveil how a critical molecule turns on T cells August 03, 2015 LA JOLLA–T cells are the guardians of our bodies: they constantly search for harmful invaders and diseased cells, ready to swarm and kill off any threats. A better understanding of these watchful sentries could allow scientists to boost the immune response

Recruiting the entire immune system to attack cancer

Stimulating both major branches of the immune system halts tumor growth more effectively. Anne Trafton | MIT News Office April 13, 2015 The human immune system is poised to spring into action at the first sign of a foreign invader, but it often fails to eliminate tumors that arise from the body’s own cells. Cancer

Newly Enlisted T-Cell ‘Policemen’ Can Slow Down Run-Away Immune System, SLU Scientist Says

March 30, 2015 Carrie Bebermeyer, Medical Center Communications, Saint Louis University ST. LOUIS — In research published in the March issue of Immunity, Saint Louis University scientists led by Daniel Hawiger, M.D., Ph.D., assistant professor of molecular microbiology and immunology, have discovered that potentially aggressive T-cells that might lead to auto-immune disease can instead be enlisted to

Immune System Boosted By Stem-Cell-Based Strategy In Mouse Model

Medical News Today, by Staff ~ May 20, 2013 Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs

UCLA Researchers Engineer Blood Stem Cells to Fight Melanoma

Monday, November 28, 2011 By: UCLA Health Sciences Researchers from UCLA's cancer and stem cell centers have demonstrated for the first time that blood stem cells can be engineered to create cancer-killing T-cells that seek out and attack a human melanoma. The researchers believe this approach could be useful in 40 percent of Caucasians with