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Color-changing Polymer May Signal Traumatic Brain Injuries in Soldiers, Athletes

Mon, 08/17/2015 - 9:37am American Chemical Society Microscopy images of the photonic crystals after nano-indentation at 30 mN (left), 60 mN (middle) and 90 mN (right) are shown. (Image: Yang lab)A bomb blast or a rough tackle can inflict brain damage that destroys lives. Yet at the time of impact, these injuries are often invisible. To

Penn Researchers Develop Custom Artificial Membranes to Study the Molecular Basis of Disease

May 7, 2015 By Madeleine Stone Decorating the outside of cells like tiny antenna, a diverse community of sugar molecules acts like a telecommunications system, sending and receiving information, recognizing and responding to foreign molecules and neighboring cells. “The sugar part of our biomembranes are as crucial to our health as our DNA, and yet we

Regenerative Medicine Study Underscores Lung Regeneration Capacity

April 28, 2015, Reid D'Amoco In diseases like cystic fibrosis, the lungs undergo constant healing and remodeling due to chronic infections. To better understand the repair mechanisms the lungs go through in diseases like CF and COPD, scientists have paid great attention to studying cellular regeneration. Scientists at the University of Pennsylvania and Duke University have discovered

First steps in basic biological process that could be harnessed to make therapeutic cells

April 16, 2015Pioneer factor binding chromosomes is shown. Credit: Kenneth S. Zaret, Ph.D., Perelman School of Medicine, University of PennsylvaniaUnderstanding the molecular signals that guide early cells in the embryo to develop into different types of organs provides insight into how tissues regenerate and repair themselves. By knowing the principles that underlie the intricate steps

Lung Cells Can Regenerate Themselves, Finding Could Bring New Disease Cures

By Jim Algar, Tech Times | April 13, 7:58 PM Type 1 cells (green) and Type 2 cells (red)Cells in lung tissue show a surprising ability to regenerate and differentiate to repair lung damage, study finds. Such a process might be stimulated to help sufferers of various lung diseases, researchers suggest. Here, Type 1 cells

A vaccination to prevent heart attacks?

Harvard Stem Cell Institute, by Staff ~ June 9, 2014 Harvard Stem Cell Institute (HSCI) scientists collaborating with researchers at the University of Pennsylvania have developed a “genome editing” approach for permanently reducing cholesterol levels in mice with a single injection, potentially reducing heart attack risk by up to 90 percent. “For the first iteration

Path of Plaque Buildup is Possible Alzheimer’s Biomarker

Relatively Early Accumulation of Plaques in Temporal Lobe Was Associated With Cognitive Decline Tue, 2013-07-16 09:34, Perelman School of Medicine, University of Pennsylvania Philadelphia - The trajectory of amyloid plaque buildup— clumps of abnormal proteins in the brain linked to Alzheimer’s disease- may serve as a more powerful biomarker for early detection of cognitive decline rather