Gene therapy has shown promise in treating inherited genetic diseases, but a major issue that has frustrated scientists remains: Replacing a “bad” gene with a healthy one often is a short-lived fix. Typically, the healthy replacement gene works for just a few weeks. Now, scientists at Washington University School of Medicine in St. Louis have
More than 10,000 people in the United States are living with memory loss and other persistent neurological problems that occur after West Nile virus infects the brain. Now, a new study in mice suggests that such ongoing neurological deficits may be due to unresolved inflammation that hinders the brain’s ability to repair damaged neurons and
Devastating consequences of Zika virus infection are suffered in the womb, where the virus can cause brain damage and sometimes death. Studying pregnant mice, researchers at Washington University School of Medicine in St. Louis have learned that the Zika virus infects the fetus by manipulating the body’s normal barrier to infection. Moreover, they showed that
Discovery provides potential target for vaccines, treatments by Tamara Bhandari By age 2, most children have been infected with respiratory syncytial virus (RSV), which usually causes only mild cold symptoms. But people with weakened immune systems, such as infants and the elderly, can face serious complications, including pneumonia and – in some cases – death.
Washington University in St. Louis, by Michael C. Purdy ~ January 30, 2014 Scientists have identified a way some viruses protect themselves from the immune system’s efforts to stop infections, a finding that may make new approaches to treating viral infections possible. Viruses have well-known strategies for slipping past the immune system. These include faking
Missourinet, by Mike Lear ~ July 1, 2013 A researcher at Washington University in St. Louis will take part in a study to look for similarities in how humans respond to three potentially lethal viruses. Washington University Professor of Medicine Michael Diamond is an expert on West Nile virus. He will work with researchers at