Washington University School of Medicine

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Zika virus kills brain cancer stem cells

While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment for glioblastoma, a deadly form of brain cancer. New research from Washington University School of Medicine in St. Louis and the University of California San Diego School of Medicine shows that the virus kills brain

Type of sugar may treat atherosclerosis, mouse study shows

Trehalose triggers cellular housekeeping in artery-clogging plaque by Julia Evangelou Strait Researchers have long sought ways to harness the body’s immune system to treat disease, especially cancer. Now, scientists have found that the immune system may be triggered to treat atherosclerosis and possibly other metabolic conditions, including fatty liver disease and type 2 diabetes. Studying

Drug believed to reduce postoperative pain and delirium does neither

MEDIA CONTACT Judy Martin Finch · martinju@wustl.edu · 314-286-0105 AUDIO https://medicine.wustl.edu/?p=43418&preview=1&_ppp=3d29f7be16 To blunt postoperative pain and reduce the need for opioid drugs following surgery, anesthesiologists often give patients low doses of the drug ketamine during operations. Recent research even suggests ketamine might alleviate postsurgical delirium and confusion in older adults. But a new study led

Antibody helps detect protein implicated in Alzheimer’s, other diseases

May lead to novel ways to diagnose, monitor brain injury by Tamara Bhandari•April 19, 2017 HUY MACH Researchers use mouse brains (above) to study ways to measure the brain protein tau, which plays a role in neurodegenerative diseases such as Alzheimer's. A team led by scientists at Washington University School of Medicine in St. Louis

Landmark Alzheimer’s prevention trial to evaluate third drug

Effort to study drug's ability to prevent, delay the disease By Tamara Bhandari December 19, 2016 Washington University School of Medicine's Randall J. Bateman, MD, talks with DIAN-TU trial participant Natalie Shriver, of Omaha, about a study to test drugs that may prevent or delay Alzheimer's disease. (Photo: Robert Boston/Washington University School of Medicine) An

Laser surgery opens blood-brain barrier to chemotherapy

Technology may improve treatment for deadly brain cancer by Jim Goodwin•February 24, 2016 ROBERT BOSTON PHOTO Washington University neurosurgeon Eric C. Leuthardt, MD, and others have discovered another benefit of laser surgery for patients with glioblastomas, one of the most difficult cancers to treat. In addition to killing the tumors with heat, the technology bypasses

Loss of support cells in brain may inhibit neuronal development

October 6, 2015 By Jim Dryden Washington University School of Medicine researchers Courtney Sobieski (left) and Steven Mennerick, PhD, found, in culture, that without cells called astrocytes, neurons send signals to one another more slowly. That slowdown could interfere with neuronal development and contribute to conditions linked to communication between neurons. Shedding light on possible

$7.3 million grant funds study of lung transplant rejection

September 17, 2015 By Caroline Arbanas Lung transplants – a treatment of last resort for end-stage lung disease – have given thousands of patients a second lease on life. But the long-term success of the procedure still lags far behind that seen in heart, liver and kidney transplants, and scientists have struggled to understand why.

Cardiac Beta-Blocker Medication Found to Increase Survival in Ovarian Cancer Patients

August 27, 2015     by Patricia Silva, Bio News Texas A study recently published in the journal Cancer revealed that beta-blocker agents can increase the survival rate in ovarian cancer patients. The study was led by researchers at The University of Texas MD Anderson Cancer Center and Washington University School of Medicine, and is

New clues found to vision loss in macular degeneration​​​

August 11, 2015 By Jim Dryden APTE LABORATORY PHOTO In this image of the retina, normal blood vessels (green) surround a clump of new, abnormal vessels that has formed beneath the center of the retina. Scientists at Washington University School of Medicine in St. Louis have identified a molecular pathway that leads to the formation